Pharmacology Flashcards
What can you use to treat neuropathic pain?
- Antidepressants: Tricyclic antidepressants, SNRIs or SSRIs
- Anticonvulsants: banapentin, pregabalin, carbamazepine
- Topical analgesics
- Canabis
- Non-pharmalogical: thermal, CBT, PT, OT, TENS, acupuncture…
What are Triptans?
Selective agonists at 5-HT 1B/1D serotonin receptor developed as a specific migraine treatment
What medication can you give to a patient with a big headache in the ER?
Metoclopramide IV
What can you prescribe for prophylactic treatment of headaches (more than 1 day/month of headache)?
- Vitamin B2 (Riboflavin) 400 mg QD
- Magnesium 600 mg QD
- Cyproheptadine (Periactin) 4 mg TID for young kids < 10
For which types of seizures is used Phentoin (Dilantin)?
Partial and generalized
Which type of medication for seizure is taken ONCE a day?
Phentoin (Dilantin)
Which type of medication is indicated for generalized seizures?
- Valproic acid (Epival)
- Phentoin (Dilantin)
- Leviteracetam (Keppra)
Which type of medication is indicated for partial seizures?
- Carbamazepine (Tegretol)
- Phentoin (Dilantin)
- Leviteracetam (Keppra)
Which seizure medication have side effects of weight gain and tremor?
Valproic Acid (Epival)
Which seizure medication have a side effect of rash?
- Carbamazepine (Tegretol)
- Phentoin (Dilantin)
Which seizure medication have pstchiatric side effects?
Leviteracetam (Keppra)
Name the types of SSRIs
- Effective–E**scitalopram*
- For–F**luoxetine, Fluvoxamine*
Sadness–Sertraline
Panic–Paroxetine
Compulsions–Citalopram
What are the indications for SSRIs?
- Major depressive disorder
- Anxiety disorders
- PTSD
- OCD
- Premenstrual dysphoric disorder
- Bulimia nervosa
- Bipolar Depression (Fluox + olanz combo)
What are the side effects of SSRIs?
- GI upset
- Headache
- Sexual dysfunction
Name the SNRIs
- Venlafaxine (Effexor)
- Desvenlafaxine (Pristiq)
- Duloxetine (Cymbalta)
- Levomilnacipran (Fetzima)
What are the indications of SNRIs?
- Depression
- Anxiety disorders
- Pain
- Energy
- Concentration
What are the side effects of SNRIs?
Noradrenergic beta-receptors
- Tremor
- Hypertension
- Tachycardia
Noradrenergic alpha-receptors
- Dry mouth
- Constipation
- Urinary retention
Sweating
What are the types of antidepressants?
- Serotonin Serum Reuptake Inhibitors (SSRIS)
- Serotonin Norepinepherine Reuptake Inhibitors (SNRIS)
- Tricyclic Antidepressants (TCAs)
- Monoamine Oxidase Inhibitors (MAOIs)
- Atypical antidepressant
What are the side effects of Monoamine Oxidase Inhibitors (MAOIs)?
Serotonin Syndrome
Hypertensive crisis
What are the indications for lithium?
- Mania (prominent irritability)
- Resistant depression: anti-suicidal
What are the common side effects of lithum?
- L – leukocytosis
- I – Inspidus (diabetes)
- T – Tremors
- H – Hypothyroid
- I – increased urine (polyuria)
- M – Mom’s beware (teratogenicity)
Which mood stabilizer medication is compatible with lactation?
Valproate
What antidepressant medication CAN’T you give to an anorexic patient?
Bupropion
What are the 2 only drugs that decrease suicidal ideations?
- Lithium
- Clozapine
What medication do you give for trigeminal neuralgia?
Carbamazepine
What medication do you give to kids with absence seizures?
Ethosuximide
What medication do we generally give for atonic and myoclonic seizures?
Valproic acid
