Pharmacology

Question 1

What can you use to treat neuropathic pain?

Answer 1

1. Antidepressants: Tricyclic antidepressants, SNRIs or SSRIs
2. Anticonvulsants: banapentin, pregabalin, carbamazepine
3. Topical analgesics
4. Canabis
5. Non-pharmalogical: thermal, CBT, PT, OT, TENS, acupuncture…

Question 2

What are Triptans?

Answer 2

Selective agonists at 5-HT 1B/1D serotonin receptor developed as a specific migraine treatment

Question 3

What medication can you give to a patient with a big headache in the ER?

Answer 3

Metoclopramide IV

Question 4

What can you prescribe for prophylactic treatment of headaches (more than 1 day/month of headache)?

Answer 4

1. Vitamin B2 (Riboflavin) 400 mg QD
2. Magnesium 600 mg QD
3. Cyproheptadine (Periactin) 4 mg TID for young kids < 10

Question 5

For which types of seizures is used Phentoin (Dilantin)?

Answer 5

Partial and generalized

Question 6

Which type of medication for seizure is taken ONCE a day?

Answer 6

Phentoin (Dilantin)

Question 7

Which type of medication is indicated for generalized seizures?

Answer 7

1. Valproic acid (Epival)
2. Phentoin (Dilantin)
3. Leviteracetam (Keppra)

Question 8

Which type of medication is indicated for partial seizures?

Answer 8

1. Carbamazepine (Tegretol)
2. Phentoin (Dilantin)
3. Leviteracetam (Keppra)

Question 9

Which seizure medication have side effects of weight gain and tremor?

Answer 9

Valproic Acid (Epival)

Question 10

Which seizure medication have a side effect of rash?

Answer 10

1. Carbamazepine (Tegretol)
2. Phentoin (Dilantin)

Question 11

Which seizure medication have pstchiatric side effects?

Answer 11

Leviteracetam (Keppra)

Question 12

Name the types of SSRIs

Answer 12

• Effective–E**scitalopram*
• For–F**luoxetine, Fluvoxamine*

Sadness–Sertraline

Panic–Paroxetine

Compulsions–Citalopram

Question 13

What are the indications for SSRIs?

Answer 13

• Major depressive disorder
• Anxiety disorders
• PTSD
• OCD
• Premenstrual dysphoric disorder
• Bulimia nervosa
• Bipolar Depression (Fluox + olanz combo)

Question 14

What are the side effects of SSRIs?

Answer 14

• GI upset
• Headache
• Sexual dysfunction

Question 15

Name the SNRIs

Answer 15

• Venlafaxine (Effexor)
• Desvenlafaxine (Pristiq)
• Duloxetine (Cymbalta)
• Levomilnacipran (Fetzima)

Question 16

What are the indications of SNRIs?

Answer 16

• Depression
• Anxiety disorders
• Pain
• Energy
• Concentration

Question 17

What are the side effects of SNRIs?

Answer 17

Noradrenergic beta-receptors

• Tremor
• Hypertension
• Tachycardia

Noradrenergic alpha-receptors

• Dry mouth
• Constipation
• Urinary retention

Sweating

Question 18

What are the types of antidepressants?

Answer 18

1. Serotonin Serum Reuptake Inhibitors (SSRIS)
2. Serotonin Norepinepherine Reuptake Inhibitors (SNRIS)
3. Tricyclic Antidepressants (TCAs)
4. Monoamine Oxidase Inhibitors (MAOIs)
5. Atypical antidepressant

Question 19

What are the side effects of Monoamine Oxidase Inhibitors (MAOIs)?

Answer 19

Serotonin Syndrome

Hypertensive crisis

Question 20

What are the indications for lithium?

Answer 20

• Mania (prominent irritability)
• Resistant depression: anti-suicidal

Question 21

What are the common side effects of lithum?

Answer 21

• L – leukocytosis
• I – Inspidus (diabetes)
• T – Tremors
• H – Hypothyroid
• I – increased urine (polyuria)
• M – Mom’s beware (teratogenicity)

Question 22

Which mood stabilizer medication is compatible with lactation?

Answer 22

Valproate

Question 23

What antidepressant medication CAN’T you give to an anorexic patient?

Answer 23

Bupropion

Question 24

What are the 2 only drugs that decrease suicidal ideations?

Answer 24

1. Lithium
2. Clozapine

Question 25

What medication do you give for trigeminal neuralgia?

Answer 25

Carbamazepine

Question 26

What medication do you give to kids with absence seizures?

Answer 26

Ethosuximide

Question 27

What medication do we generally give for atonic and myoclonic seizures?

Answer 27

Valproic acid