Pharmacology Flashcards
1
Q
What is zero order kinetics?
A
rate of elimination is constant
(not dependent of drug amount)
this means that the clearance system can saturate
2
Q
Which drugs exhibit zero order kinetics?
A
- phenytoin
- alcohol
- salicylates
3
Q
What is first order kinetics?
A
linear process
rate of elimination is proportional to drug concentration
i.e. higher the [drug], the higher the rate of elimination
