Pharmacology Flashcards
What is Pharmacodynamics
Pharmacodynamics is the effects the drugs have in the body
What is pharmacokinetics?
Pharmacokinetics is the effect the body has on the drug.
What does ADME stand for?
Absorption
Distribution
Metabolism
Excretion
What is meant by First Pass Metabolism?
First Pass Metabolism is where the drug concentration is greatly reduced before it reaches the systemic circulation.
What is Bioavailability?
The proportion of a drug that enters the circulation when introduced into the body so can have an active effect.
What is Pharmacology
The study of drugs and their interactions with the body.
What 2 organs are the most important to consider the functions of when prescribing certain medications for certain groups?
Liver - Metabolism
Kidneys - Excretion
Explain the significance of a black Triangle next to a drug in the BNF?
New or monitored drugs that are under surveillance.
Who do you report Adverse drug reactions to?
Medicines Healthcare products Regulatory Agency (MHRA) via the yellow card scheme
What does EGFR mean and what is its significance?
ESTIMATED GLOWMERULAR FILTRATION RATE.
Indicates renal function
How well the kidneys are functioning and can filtrate toxins.
If prescribing for a child what is specifically important?
Weight
Who has a larger % of body fat?
Women
What are Advisory labels?
Advice and cautions on medications when dispensed.
Where do you find Advisory labels in the BNF?
Advisory Labels are detailed in
“Medicinal Forms”
What do Alpha Blockers do?
They are used to lower blood pressure and usually end in “zosin”
