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LC > pharmacology > Flashcards

pharmacology Flashcards

1
Q

Which drugs decrease in absorption with age?

A

warfarin and PCN

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2
Q

Which drugs increase in absorption with age?

A

TCAs, Benzos, opioids, anticonvuslants

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3
Q

Inappropriate early release of enteric drug with age?

A

aspirin

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4
Q

Which drugs cause slowed GI motility

A

Diphenhydramine, TCAs

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5
Q

Which drugs increase gastric emptying and GI motility?

A

metacloprimide, diarrhetics

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6
Q

What is unchanged with age: rate or extent of absorption?

A

extent of absorption

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7
Q

Examples of water soluble drugs

A

digoxin, aminoglycosides, and lithium

lower volume of distribution- lower loading dose

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8
Q

Examples of lipid soluble drugs

A

chlordiazepoxide, diazepam

Increase volume of distribution

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9
Q

Examples of drugs that use first pass metabolism

A

nitrates, propanolol, lidocaine, phenobarbitol, and nifedipine

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10
Q

By how much do phase 1 slow by?

A

30-35%
chlordiazepoxide
diazepam

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11
Q

Name some phase 2 reactants (minimally affected)

A

lorazepam
oxazepam
timezepam

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LC (2 decks)

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