Pharmacology Flashcards by Anne Geller

Q

is hydroxylation p450 dependent or indpendent

A

dependent

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Q

is Oxidation p450 dependent or indpendent

A

dependent

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Q

is oxidative dealkylation p450 dependent or indpendent

A

dependent

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Q

is deamination p450 dependent or indpendent

A

dependent

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Q

is dehydrogenation p450 dependent or indpendent

A

indpendent

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Q

is hydrolysis p450 dependent or indpendent

A

indpendent

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Q

is reduction p450 dependent or indpendent

A

indpendent

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Q

phase I or II: glucuronidation

A

phase II

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Q

phase I or II: acetylation

A

phase II

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Q

phase I or II: glutathione

A

phase II

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Q

phase I or II: phosphoadenosyl

A

phase II

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Q

phase I or II: sulfination

A

phase II

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Q

phase I or II: methylation

A

phase II

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Q

Vd =

A

amount of drug in the body / plasma conc of drug

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Q

Cl =

A

rate of elimination / concentration

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Q

t(1/2)`

A

.7*Vd / Clearance

Q

henderson hasselbach

A

pH = pKa log [U/P]