Pharmacology Flashcards
Enforces control of drugs
DEA
FDA
Drug strength and purity. Guidelines for drug labeling. Ensure drug safety if used as label directs. Development and approval.
Drug strength and purity. Guidelines for drug labeling. Ensure drug safety if used as label directs. Development and approval.
FDA
CVM
Ensures approved vet meds will not harm animals
Ensures approved vet meds will not harm animals
CVM
What did the controlled substance act of 1970 do?
Defined drug abuse as the illicit use of an illegal drug or the improper use of a legal Rx drug; classifies controlled drugs into one of 5 schedules/classes;
What is the definition of drug abuse?
the illicit use of an illegal drug or the improper use of a legal Rx drug
How often do DVM’s have to register with the DEA?
Every 3 years to use or prescribe controlled substances
What does a DVM receive from the DEA so they can order and prescribed controlled substances?
DEA number assigned
How do controlled substances need to be stored?
In a locked cabinet
How long do records need to be kept for ordering, use and dispensing of controlled substances?
2 years
How often does inventory have to be submitted to the DEA?
q 2 years
EPA
Development and approval of topical pesticides
Development and approval of topical pesticides
EPA
USDA
Development and approval of biologics such as vaccines and antitoxins
Development and approval of biologics such as vaccines and antitoxins
USDA
Toxicity evaluation
Determine the dose a drug induces organ or tissue damage that may result in permanent injury or death
Determine the dose a drug induces organ or tissue damage that may result in permanent injury or death
Toxicity evaluation
Effective dose
Amount of drug or dose produces desired effect
Amount of drug or dose produces desired effect
Effective dose
Lethal dose
Dose of a drug that kills 50% of the animals that receive it
Dose of a drug that kills 50% of the animals that receive it
Lethal dose
Therapeutic index -margin of safety
Drug dose that produces desired effect with minimal or no signs of toxicity
Drug dose that produces desired effect with minimal or no signs of toxicity
Therapeutic index - margin of safety
DEA
Enforces control of drugs
What should instructions include?
Date and time of order -to be given
Drug name
Drug dosage (dose, route, frequency, duration)
Signature of prescriber (or verbal instructions)
What are the six rights of drug administration?
Patient, dose, drug, time, route, documentation
What is therapeutic range?
Drug concentration in the body that produces the desired effect in the patient with minimal or no signs of toxicity
What are the three routes of administration?
Parenteral (injections, not absorbed by GI tract)
Nonparenteral (PO or absorbed by GI tract)
Locally (given where works)
What are causes of drug toxicity?
Outright (dose too high, too long, too frequent)
Relative (recommended dose too high for specific pt)
Side effects (may occur at higher levels)
Accidental exposure
Interaction w/other drugs
Incorrect Tx-misdiagnosed
What must be included on a drug label?
Drug names (generic and trade) concentration and quantity Name and address of manufacturer Manufacturer's control or lot number Expiration date Withdrawal time (if warranted) Controlled substance status (if warranted)
