Pharmacology Flashcards
drugs ending in -zole ware what class
PPI
Misoprostol mechanism
PGE1 analog decreases acid production
Sulfasalazine toxicity
Reversible oligospermia
Metoclopramide mechanism
D2 blocker increases contractility and motility proximal to the colon
bismuth, sucralfate clinical use
ulcer healing, traveler’s diarrhea
Misoprostol toxicity
diarrhea
Drugs ending in -dine are what class
H2 blocker
MgOH toxicities
- Diarrhea
- decreased DTRs
- hypotension
- cardiac
CaCO3 toxicities
- hypercalcemia
- chelate and decrease efficacy of tetracyclines
PPI toxicities
- increased C diff risk
- lowers Mg2+
ondansetron toxicities
- prolonged QT
- HA
- constipation
ondansetron mechanism
5HT3 antagonist decerases vagal stimulation
Bismuth, sucralfate mechanism
increases bicarb secretion at ulcer base
Octreotide clinical use
variceal bleeds
acromegaly
VIPoma
carcinoid tumors
Misoprostol clinical use
prevent NSAID associated gastric ulcers