Pharmacology Flashcards

1
Q

What are alternatives for pt with penicillin allergy?

A

Clinca, Vanco, Cipro, Levaquin

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2
Q

What antibiotics cover Pseudomonas?

A

Fortaz, Aztreonam, Timentin, Cipro, Ceftazidime, Cefepime, Imipenem, Aminoglycosides, Zosyn

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3
Q

What are the FDA approved antibiotics for MRSA?

A

Vanco, Linezolid, Daptomycin, Tigecyclin, Telavancin

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4
Q

What are the FDA approved antibiotics for diabetic foot infections?

A

Zosyn, Zyvox, Invanz

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5
Q

What antibiotics are metabolized by the liver?

A

Clindamycin, Cefoperazone, Chloramphenicol, Erythromycin

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6
Q

What is the MOA of aminoglycosides?

A

Bind 30s subunit of RNA

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7
Q

What is the MOA of macrolides?

A

Bind 50s subunit of RNA

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8
Q

What antibiotics can cause tendon ruptures with long term use and are contraindicated in children?

A

Quinolones

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9
Q

What are adverse reactions of aminoglycosides?

A

Nephrotoxicity, ototoxicity, neuromuscular blockade

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10
Q

What antibiotic is MC cause of pseudomembranous colitis?

A

Clindamycin

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11
Q

What is dose of lamasil for onychomycosis?

A

250mg/day for 12 weeks

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12
Q

How do you calculate Crt clearance?

A

(Wt in kg)(140-age)(0.85 if female)/(72)(crt)

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13
Q

What is the cause of erythrasma?

A

Corynebacterium minutissimum

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14
Q

What is used to treat erythrasma?

A

Erythromycin

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15
Q

Name some aerobic, gm+ cocci

A

Staph, strep, enterococcus

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16
Q

Name some aerobic, gm+ rods

A

Bacillus, corynebacterium, listeria

17
Q

Name some aerobic, gm- rods

A

Pseudomonas, E. coli, shigella, salmonella, klebsiella

18
Q

Name some aerobic, gm- cocci

A

Neisseria

19
Q

Name an anaerobic, gm+ cocci

A

Peptostreptococcus

20
Q

Name an anaerobic, gm+ rod

A

Clostridium

21
Q

Name an anaerobic, gm- rod

A

Bacteroides