Pharmacology Flashcards
What are alternatives for pt with penicillin allergy?
Clinca, Vanco, Cipro, Levaquin
What antibiotics cover Pseudomonas?
Fortaz, Aztreonam, Timentin, Cipro, Ceftazidime, Cefepime, Imipenem, Aminoglycosides, Zosyn
What are the FDA approved antibiotics for MRSA?
Vanco, Linezolid, Daptomycin, Tigecyclin, Telavancin
What are the FDA approved antibiotics for diabetic foot infections?
Zosyn, Zyvox, Invanz
What antibiotics are metabolized by the liver?
Clindamycin, Cefoperazone, Chloramphenicol, Erythromycin
What is the MOA of aminoglycosides?
Bind 30s subunit of RNA
What is the MOA of macrolides?
Bind 50s subunit of RNA
What antibiotics can cause tendon ruptures with long term use and are contraindicated in children?
Quinolones
What are adverse reactions of aminoglycosides?
Nephrotoxicity, ototoxicity, neuromuscular blockade
What antibiotic is MC cause of pseudomembranous colitis?
Clindamycin
What is dose of lamasil for onychomycosis?
250mg/day for 12 weeks
How do you calculate Crt clearance?
(Wt in kg)(140-age)(0.85 if female)/(72)(crt)
What is the cause of erythrasma?
Corynebacterium minutissimum
What is used to treat erythrasma?
Erythromycin
Name some aerobic, gm+ cocci
Staph, strep, enterococcus