Pharmacology

Question 1

Amoxicillin

Answer 1

-abx
-extended spectrum penicillin
use:
-mild-mod BACTERIAL infxn
key:
-cell wall synthesis inhibitor
-GOOD against strep
-synergistic w/ aminoglycosides
ADR:
-GI, hypersensitivity
DI:
-bacteriostatic abx
-OCPs

Question 2

Amoxcillin w/ Clavulanate

Answer 2

-amox w/ beta lactamase
use:
-mild-mod BACTERIAL infxn
ADR:
-GI, hypersensitivity 
DI:
-bacteriostatic abx
-OCPs

Question 3

Azithromycin

Answer 3

-macrolide (abx)
-alt to penicillin
-protein synthesis inhibitor
-active against ATYPICAL (some gram +/-)
ADR:
-GI, hypersensitivity, PROLONGED QT interval
DI:
-none

Question 4

Trimethoprim & TMP-SMX

Answer 4

-mild-mod BACTERIAL infxn
-combo to disrupt DBA syntehsis
use:
-UTI
-acute otitis media
-skin infxn
ADR:
-GI, hypersensitivyt, HEMTAOLOGIC ABNORMALITIES, PREGNANCY
DI:
-CYP 450 inhibition
-ADR duplication
-displacement of protein binding

Question 5

Levofloxacin

Answer 5

-mild-mod BACTERIAL infxn
-inhibits DNA synthesis
-GREAT against gram + –> GOOD against gram - & atypical coverage
use:
-pyelonephritis, UTI, PNEUMONIA
ADR:
-GI, tendon, CNS, hypersenitivity, photosensitivity
DI:
-cation containing
-OCPs

Question 6

Ceftriaxone

Answer 6

-mod - severe BACTERIAL infxn
-3rd gen cephlasporin: gram -&raquo_space; gram +
-inhibits protein synthesis
-administer IV/IM
ADR:
-injection rxn
-GI, hypersensitivity
-KIDNEY damage
-CDAD
DI:
-alcohol
-anticoagulants
-OCPs

Question 7

Triamcinolone

Answer 7

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