Pharmacology Flashcards
Non-proprietary name, Abbreviated, Common, Cheaper to purchase
Generic Drug Name
Precise description of the drug’s chemical composition and molecular structure.
Chemical Drug Name
Followed by the initials “USP” or “NF”
Usually the same as one of the other drug names.
Official Drug Names
Brand or proprietary name, trademark, first letter is Capitalized, Named by the manufacturer of drug.
Trade Drug Name
Motrin, Advil
ibuprofen, USP
ibuprofen
(RS)-2-(4-(2-methylpropyl)pheny)propanoic acid
Trade or Brand Name
Official Name
Generic Name
Chemical Name
Schedule I
No recognized medical use; high abuse potential
EX: Opiates (heroin), hallucinogens (LSD), depressants (methaqualone)
Schedule II
Written prescriptions required; no telephone renewals.
EX: Opiates (codeine, morphine, meperidine), stimulants (amphetamines), depressants
Schedule III
Prescriptions rewritten after 6 months or five refills.
EX: Opiates (codeine <1.8g/dl), stimulants, depressants, anabolic steroids.
Schedule IV
Prescriptions rewritten after 6 months or 5 refills.
EX: Opiates (propoxyphene), stimulants, depressants (chloral hydrate)
Schedule V
Any non-narcotic medication, OTC
EX: Small amounts of opiates when used as antitussives or antidiarrheals.
Pharmacokinetics
Drug movement thru the body.
Pharmacodynamics
How a drug acts on a living organism.
Biotransformation
Chemical changes drug goes thru at its metabolized.
Proteins embedded in the cell that combine with drug for effect.
Receptors
Specific site of action.
Receptor Site
Force of attraction or binding strength of receptor and drug.
Affinity
Drug’s ability to cause expected results.
Efficacy
Drug that binds to receptor.
Agonist
Drug that binds to receptor and blocks effects of others.
Antagonist
Relay signals from the receptor site to target molecules inside the cell.
Second Messenger
Drug’s progress from its pharmaceutical dosage form to a biologically available substance.
Drug Absorption
Define Half-life.
Time it takes to metabolize 50% of the drug.
Define Bolus.
Concentrated single dose.
Define Loading Dose.
Bolus given to rapidly attain therapeutic plasma levels.
Define Maintenance Dose.
Amount of drug needed to maintain a steady therapeutic plasma concentration.
What is, the the degree to which a substance is poisonous.
At high doses, drugs can produce toxic effects that are not seen at low dosage.
Toxic Level/Toxicity
