Pharmacology Flashcards
0
Q
What type of drug would you give to an individual to decrease thyroid hormone synthesis?
A
A Na/I cotransport blocker. ( i.e. Perchlorate or thiocyanate)
1
Q
Name two Na/I cotransport blockers.
A
- Perchlorate
2. Thiocyanate
2
Q
What medication can be given to treat and individual with hyperthyroidism?
A
Propylthiouracil (PTU)
This blocks the synthesis by blocking all three functions of thyroid peroxidase. (1. Oxidation of I- to I2, 2.organification of I2 to thyroglobulin and 3. Coupling reactions)
