Pharmacology Flashcards
Labetalol
ANTIHYPERTENSIVE
Mechanism of action:
Alpha and beta adrenergic blocker
(non selective)
Competitively blocks beta receptors in heart, peripheral vasculature, bronchi, pancreas, uterus, kidney, brain and liver
Dosing:
Side effects:
Contra-indications:
- Severe asthma
Nifedipine
ANTIHYPERTENSIVE
Mechanism of action:
Calcium channel blocker
Block inward current of calcium into cells in vascular smooth muscle, myocardium and cardiac conducting system via L-type calcium channels
Side effects:
Contra-indications:
Methyldopa
ANTIHYPERTENSIVE
Mechanism of action:
Centrally acting alpha 2 adrenergic receptor agonist
Reduces blood pressure by reducing sympathetic tone
Dosing:
Side effects:
Contraindications: