Pharmacology Flashcards
What are the mechanisms through which drugs are processed by the body?
Liberation, Absorption, Distribution, Metabolization, Excretion
What is the first mechanism when a drug is processed by the body?
Liberation
What is the second mechanism when a drug is processed by the body?
Absorption
What is the third mechanism when a drug is processed by the body?
Distribution
What is the fourth mechanism when a drug is processed by the body?
Metabolization
What is the final mechanism when a drug is processed by the body?
Excretion
What is the mechanism for when the drug separates from the inactive ingredients?
Liberation
What is liberation?
The mechanism through which a drug separates from inactive ingredients
Complete the list:
_______ > Absorption > Distribution > Metabolism > Excretion
Liberation
What is the mechanism for when the drug begins entering the blood?
Absorption
What is absorption?
When the drug enters the blood
What is bioavailability?
The percentage of a drug that actually enters the blood
What is the term for the percentage of a drug that actually enters the blood?
Bioavailability
What reduces a drug’s bioavailability?
When a drug has to pass through the mucous membranes and GI tract
What can be changed about a drug to change its onset and duration of action?
Liberation
What type of drugs are subject to the first-pass effect?
Drugs taken orally
What is the first-pass effect?
The breakdown of drugs before they reach circulation
What is the term for the breakdown of drugs before they reach circulation?
First-pass effect
What is the mechanism where a drug becomes dispersed around the body?
Distribution
What is distribution?
When a drug becomes dispersed around the body
Complete the list:
Liberation > _______ > Distribution > Metabolism > Excretion
Absorption
What is Metabolism?
The breakdown of a drug