Pharmacology

Question 1

Mechanism of action of clindamycin?
Good at treating…?

Answer 1

Inhibits protein synthesis

Is a lincosamide (MYCIN) antibiotic

Treats gram positive cocci e.g. streptococci or penicillin-resistant staphylococci

Question 2

Mechanism of action of quinolones e.g. ciprofloxacin, levofloxacin

Answer 2

Inhibits bacterial mRNA synthesis - halts bacterial proliferation

Also rifampicin

Question 3

Mechanism of sulphonamides e.g. trimethoprim, sulfamethoxazole?

Answer 3

Inhibiting folate synthesis

Question 4

Mechanism of beta-lactams e.g. amoxicillin, co-amoxiclav?

Answer 4

Inhibits bacterial cell wall synthesis

Also vancomycin