Pharmacology

Question 1

What is a bisphosphonate drug that treats patients with Paget’s disease by inhibiting the activity of osteoclasts?

Answer 1

Alendronate

Question 2

Which IV anesthetic is classified as a dissociative agent and is often used for conscious sedation?

Answer 2

Ketamine

Question 3

Which cardiovascular drug lengthens the QT interval and prolongs the QRS complex?

A. Esmolol
B. Procainamide
C. Adenosine
D. Labetolol
E. Magnesium sulfate

Answer 3

B. Procainamide

Question 4

Which antifungal drug has an adverse drug reaction that causes the patient to experience a fever and chills?

Answer 4

Amphotericin B

Question 5

What is the mechanism of action of acyclovir?

Answer 5

Inhibition of viral DNA synthesis via incorporation into replicating DNA and chain termination

Question 6

What is the mechanism of action for vancomycin?

Answer 6

Cell wall synthesis inhibition

Question 7

What drug should be used initially to treat hypertension in a patient with benign prostatic hyperplasia and urinary retention?

Answer 7

Zonsins - prazosin, doxazosin

Question 8

A patient presents to the clinic with severe cellulitis. Cultures come back positive for VRE. What is the antibiotic of choice for this patient?

Answer 8

Linezolid

Question 9

Which of the following drugs decreases reabsorption of sodium and chloride in the distal convoluted tubule?

A. Furosemide
B. Spironolactone
C. Chlorothiazide
D. Amiloride

Answer 9

C. Chlorothiazide

The loss of these ions causes increased urine volume by causing water to leave the blood as it follows sodium and chloride

Question 10

List the following drugs affinity to the correct alpha receptors

Doxazosin
Phentolamine
Prazosin
Yohimbine
Tolazoline

Answer 10

Doxazosin - alpha 1
Phentolamine - equal affinity for both alpha 1 and 2
Prazosin - alpha 1
Yohimbine - alpha 2
Tolazoline - alpha 2