Pharmacology

Question 1

Trimethoprim effects on renal function

Answer 1

Leads to a transient rise in creatinine levels by reducing the creatinine excretion of the kidneys.

Does NOT reflect the actual GFR and therefore is not reflective of AKI but rather the calculated eGFR due to a transient rise in Creatinine

Question 2

Seizure threshold lowering drugs

Answer 2

Abx: Imipenem, penicillins, cephalosporins, metronidazole, isoniazid
Antipsychotics
Antidepressants: Bupropion, Tricyclics, Venlafaxine
Tramadol
Fentanyl
Ketamine
Lidocaine
Lithium
Antihistamines