Pharmacology Flashcards

0
Q

Venous drainage for SUBLINGUAL ROUTE?

A

Lingual Vein -> Internal Jugular Vein -> Brachiocephalic (Innominate) Vein -> Superior Vena Cava -> Right Atrium
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Drugs that induce AGRANULOCYTOSIS?

A
Clozapine
Cotrimoxazole
Colchicine
Aminopyrine
Phenylbutazone
PTU
Tocaimide
Indomethacin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drugs with NARROW therapeutic index?

A
MNEMONICS:
WALA na Cyang PaPa! VasTeD na! 
----------------
Warfarin
Aminoglycoside
Lithium
Amphotericin B 
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Theophylline
Digoxin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Drugs that cause CUTANEOUS FLUSHING?

A
MNEMONICS:
VANC
----------------
Vancomycin
Adenosine
Niacin
Calcium Channel Blockers
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Drugs that induce LUPUS?

A
MNEMONICS:
HIPPP
----------------
Hydralazine
Isoniazid
Procainamide
Penicillamine
PTU
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drugs causing GINGIVAL HYPERPLASIA?

A
MNEMONICS:
NapaCa Pangit ng GingiVa mo!
----------------
Nifedipine
Cyclosporine
Phenytoin
Verapamil
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drugs that cause ERECTILE DYSFUNCTION?

A
MNEMONICS:
SORE PEniS can't Fuck Hard!
----------------
SSRI's
Optiates
Risperidone
Ethanol
Propanolol
Estrogen
Spironolactone
Finasteride
HCTZ
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drugs that have ZERO ORDER KINETICS?

A
MNEMONICS:
WHAT PET
----------------
Warfarin
Heparin
Aspirin
Tolbutamide
Phenytoin
Ethanol
Theophylline
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Drugs that cause DISULFIRAM REACTION?

A
Chlorpropamide
Cefoperazone
Cefotetan
Cefomandole
Procarbazine
Metronidazole
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drugs that are CP450 INDUCERS?

A
MNEMONICS:
Ethel Booba take Phen-Phen and Refuses Greasy Carb ShakeS.
----------------
Ethanol
Barbiturates
Phenytoin
Phenobarbital
Rifampicin
Griseofulvin
Carbamazepine
St. John Wort
Smoke
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Drugs that are CP450 INHIBITORS?

A
MNEMONICS:
Queen V's SICK RAGE
---------------- 
Quinidine
Valproic Acid
Sulfonamides
Isoniazid
Cimetidine
Ketoconazole
Ritonavir
Amiodarone
Grapefruit Juice
Erythromycin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
Erythromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

It is a sudden decrease in the response to a drug after its administration?

A

Tachyphylaxis
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Drugs causing TACHYPHYLAXIS?

A
Metoclopramide
Ephedrine
Dobutamine
Desmopressin
LSD
Calcitonin
Nitroglycerine
Nicotine
Hydralazine
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Treatment for ALCOHOLISM?

A
Disulfiram
Acamprosate
Naltrexone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Drugs causing GYNECOMASTIA?

A
MNEMONICS:
Some Drugs Create Awesome Knockers!
----------------
Spironolactone
Digoxin
Cimetidine
Alcohol
Ketoconazole
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Drugs that cause PRIAPISM?

A
MNEMONICS:
Tigas PeniS Co, AyaW Bumaba!
----------------
Trazodone
Papaverine
Sildenafil
Quetiapine
Alprostadil
Warfarin
Bupropion
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Drugs that induce HYPERTHYROIDISM?

A
Clofibrate
Amiodarone
Methadone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Drugs that induce PARKINSONISM?

A
Reserpine
Typical Antipsychotics
Methylphenyltetrahydropyridine
                 (MTPT)
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Triad for BRONZE DIABETES (Hemochromatosis)?

A
Diabetes Mellitus
Cirrhosis
Skin Pigmentation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Treatment for HEMOCHROMATOSIS?

A
Phlebotomy
Deferoxamine
Deferasirox
Deferiprone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Signs and symptoms for ORGANOPHOSPHATE POISONING?

A
MNEMONICS:
DUMBBELSS
----------------
Diarrhea
Urination
Myosis
Bronchospasms
Bradycardia
Excitation
Lacrimation
Sweating
Salivation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Toxic effects of AMIODARONE?

A
Pulmonary Fibrosis
Paresthesia
Tremors
Thyroid Dysfunction
Corneal Deposits
Skin Deposits
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Andrenergic receptors and functions?

A
Alpha 1 - vasoconstriction
Beta 1 - increase heart rate and    
              contractility
Beta 2 - vasodilation and 
              bronchodilation
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Serotonin Syndrome?

A
MNEMONICS: 
FD CHAT
----------------
Fever
Diaphoresis
Clonus
Hyperreflexia
Agitation
Tremor
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Treatment for SEROTONIN SYNDROME?

A

Cyproheptadine
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Antidote for ORGANOPHOSPHATE POISONING?

A
Pralidoxime - if within 6 hrs
Atropine
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

It is an acute episode of DELIRIUM that is usually 48-72 hrs after withdrawal from ALCOHOL?

A

Delirium Tremens
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Signs and symptoms of DELIRIUM TREMENS?

A
Hallucinations
Autonomics Hyperactivity
Delirium
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Drug of choice for DELIRIUM TREMENS?

A

Benzodiazepines
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Vitamin deficiency for Wernicke Korsakoff Syndrome?

A

Thiamine (Vit. B1) Deficiency
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

31
Q

Wernicke Korsakoff Syndrome?

A
Ataxia
Confusion
Opthalmoplegia
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
32
Q

It is a common skin finding consisting of a mottled reticulated vascular pattern that appears like a lace-like purplish discoloration of the skin?

A

Livedo Reticularis
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

33
Q

Drugs causing LIVEDO RETICULARIS?

A
Amantadine
Hydroxyurea
Minocycline
Gemcitabine
Quinidine
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
34
Q

Drugs effective at DECREASING TRIGLYCERIDES and VLDL and INCREASING HDL?

A
Niacin
Fibrates
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
35
Q

Drugs most effective at DECREASING LDL and CHOLESTEROL?

A
MNEMONICS:
NERS
----------------
Niacin
Ezetimibe
Resins
Statins
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
36
Q

Potassium Sparing Diuretics?

A
MNEMONICS:
K STAEs
----------------
Spironolactone
Triamterene
Amiloride
Eplerenone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
37
Q

Side effects of THIAZIDE DIURETICS?

A
MNEMONICS:
hyper GLUC
----------------
hyperGlycemia
hyperLipidemia
hyperUricemia
hyperCalcemia
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
38
Q

Side effects of LOOP DIURETICS?

A
MNEMONCS:
OH DANG!
---------------
Ototoxicity
Hypokalemia
Dehydration
Allergy to sulfa drugs
Nephritis
Gout
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
39
Q

Antibiotics that are BACTERIOSTATIC?

A
MNEMONIC:
ECSTaTiC
--------------
Erythromycin
Clindamycin
Sulfamethazole
Trimetoprim
Tetracycline
Chloramphenicol
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
40
Q

Extended Spectrum PENICILLINS coverage?

A
MNEMONICS:
Penicillins HELPS kill Enterococci
----------------
H. influenzae
E. coli
L. monocytogenes
P. mirabilis
Salmonella
Enterococci
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
41
Q

Antibiotics that are BACTERICIDAL?

A
MNEMONICS:
VAMPFire
----------------
Vancomycin
Aminoglycosides
Metronidazole
Penicillins
Flouroquinolones
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
42
Q

Antibiotics that are PROTEIN SYNTHESIS INHIBITORS?

A
MNEMONICS:
buy AT 30s, CELLS at 50s
----------------
30s 
  Aminoglycosides
  Tetracyclines
50s
  Chloramphenicol
  Erythromycin
  Lincosamides
  Linezolid
  Streptogramins
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
43
Q

FUNGICIDAL Antifungals?

A
Amphotericin 
Nystatin
Terbinafine
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
44
Q

Antibiotics of LAST RESORT?

A
MNEMONICS:
I AM your Last Shot at Victory
----------------
Imepenem
Amikacin
Meropenem
Linezolid
Streptogramins
Vancomycin
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
45
Q

Cephalosporins with ANTIPSEUDOMONAL ACTIVITY?

A
3rd
   Ceftazidime
   Cefoperazone
4th
   Cefepime
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
46
Q

Phase 1 Reactions?

A
MNEMONICS:
a HORDe of reactions.
----------------
Hydrolysis
Oxidation
Reduction
Deamination
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
47
Q

Drug induced PULMONARY FIBROSIS?

A
Bleomycin
Busulfan
Bromocriptine
Amiodarone
Nitrofurantoin
Methotrexate
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
48
Q

Antidote for METHOTREXATE?

A

Leucoverin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

49
Q

Antidote for CYCLOPHOSPHAMIDE?

A

Mesna
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

50
Q

Antidote for DOXORUBICIN?

A

Dexrazoxane
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

51
Q

Antidote for CISPLATIN?

A

Amifostine
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

52
Q

Cancer chemotherapy drugs acting on M PHASE?

A
Vinblastine
Vincristine
Paclitaxel
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
53
Q

Cancer chemotherapy drugs acting on G2 PHASE?

A

Bleomycin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

54
Q

Chemotherapy regimen for HODGKIN’S LYMPHOMA?

A
MNEMONICS:
MOPP(original)
ABVD(current)
----------------
Mustargen
Oncovin (Vincristine)
Procarbazine
Prednisone
Adriamycin
Bleomycin
Vinblastine
Dacarbazibe
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
55
Q

Chemotherapy regimen for NON-HODGKINS LYMPHOMA?

A
MNEMONICS:
CHOP
----------------
Cyclophosphaminde
Hydroxydaunorubicin
Oncovin (Vincristine)
Prednisone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
56
Q

Drug induced PULMONARY FIBROSIS?

A
Bleomycin
Busulfan
Bromocriptine
Amiodarone
Nitrofurantoin
Methotrexate
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
57
Q

Antidote for METHOTREXATE?

A

Leucoverin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

58
Q

Antidote for CYCLOPHOSPHAMIDE?

A

Mesna
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

59
Q

Antidote for DOXORUBICIN?

A

Dexrazoxane
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

60
Q

Antidote for CISPLATIN?

A

Amifostine
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

61
Q

Cancer chemotherapy drugs acting on M PHASE?

A
Vinblastine
Vincristine
Paclitaxel
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
62
Q

Cancer chemotherapy drugs acting on G2 PHASE?

A

Bleomycin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

63
Q

Chemotherapy regimen for HODGKIN’S LYMPHOMA?

A
MNEMONICS:
MOPP(original)
ABVD(current)
----------------
Mustargen
Oncovin (Vincristine)
Procarbazine
Prednisone
Adriamycin
Bleomycin
Vinblastine
Dacarbazibe
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
64
Q

Chemotherapy regimen for NON-HODGKINS LYMPHOMA?

A
MNEMONICS:
CHOP
----------------
Cyclophosphaminde
Hydroxydaunorubicin
Oncovin (Vincristine)
Prednisone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
65
Q

Drug induced PULMONARY FIBROSIS?

A
Bleomycin
Busulfan
Bromocriptine
Amiodarone
Nitrofurantoin
Methotrexate
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
66
Q

Antidote for METHOTREXATE?

A

Leucoverin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

67
Q

Antidote for CYCLOPHOSPHAMIDE?

A

Mesna
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

68
Q

Antidote for DOXORUBICIN?

A

Dexrazoxane
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

69
Q

Antidote for CISPLATIN?

A

Amifostine
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

70
Q

Cancer chemotherapy drugs acting on M PHASE?

A
Vinblastine
Vincristine
Paclitaxel
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
71
Q

Cancer chemotherapy drugs acting on G2 PHASE?

A

Bleomycin
__________________
Jan Patrick Ng, M.D.
Darleen Sy, M.D.

72
Q

Chemotherapy regimen for HODGKIN’S LYMPHOMA?

A
MNEMONICS:
MOPP(original)
ABVD(current)
----------------
Mustargen
Oncovin (Vincristine)
Procarbazine
Prednisone
Adriamycin
Bleomycin
Vinblastine
Dacarbazibe
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.
73
Q

Chemotherapy regimen for NON-HODGKINS LYMPHOMA?

A
MNEMONICS:
CHOP
----------------
Cyclophosphaminde
Hydroxydaunorubicin
Oncovin (Vincristine)
Prednisone
\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_\_
Jan Patrick Ng, M.D.
Darleen Sy, M.D.