Pharmacology

Question 1

What do agonist drugs do?

What do Antagonist drugs do?

Answer 1

Facilitate effect of NT when it binds to the receptor.

Block the effect of the receptor.

Question 2

What does Opium bind do?

Answer 2

Receptors located in the periaqueductal grey (connects 3 + 4 ventricle) location of many opioid receptors.

Question 3

What are endogenous opiods?

Answer 3

Naturally occurring opioids, all are neuropeptide with metabotropic receptors

Question 4

Name some endogenous opioids.

Answer 4

Enkephalins - Neuropeptides that act as opioids in the body

Endorphins - endogenous and morphine

Question 5

What are two different acetylcholine receptors?

Answer 5

Nicotine and muscarine bind to two different kinds of acetylcholine receptors

Nicotinic (ionotropic) and muscarinic (metabotropic receptors)

Question 6

What are receptors called that bind to acetylcholine NT called?

Answer 6

Cholinergic receptors

Question 7

What does atropine do to cholinergic receptors?

Answer 7

Antagonist, stopping ace from binding to muscarinic receptors in CNS. Has effect on memory,

Question 8

What is curare and what does it do?

Answer 8

Binds to nicotinic receptors, receptor blocker, prevents other NT from binding to this receptor, antagonistic effect , prevents signals between neurons and muscles and paralysis muscles.

Question 9

What are two Anti schizophrenic drugs from 1950s?