Pharmacology

Question 1

Beta lactam antibiotics include _______ & _______ .

Answer 1

penicillins cephalosporins

Question 2

How do beta lactam antibiotics interfere with cell wall synthesis?

Answer 2

Beta lactam binds to penicillin binding protein, rendering the DD-transpeptidase unable to bind to the a corresponding NAG or NAM.

Question 3

Beta lactam antibiotics are similar in structure to transpeptidas. As such beta lactams bind penicillin binding proteins rending them unable to bind to the corresponding layer of peptidoglycan. In this way beta lactams interfere with what?

Answer 3

Bacterial cell wall synthesis.

Question 4

Aztreonam is most effective against what class of bacteria?

Answer 4

Gram negative

Question 5

Aztreonam is not effective against what two types of bacteria?

Answer 5

Ineffective against Gram + and anaerobic bacteria.

Question 6

S. pyogenes remains uniformly susceptible to what antibiotic?

Answer 6

penicillin

Question 7

Penicillin remains the drug of choice for the empirical treatment of streptococcal infections due to what species?

Answer 7

S. pyogenes

Question 8

Penicillin resistance in S. pneumoniae is caused by altered what?

Answer 8

PBPs