Pharmacological therapy Flashcards
Which drug should not be co-prescribed with methotrexate?
Trimethoprim / co-trimoxazole - increases risk of marrow aplasia
How should folic acid be taken with methotrexate?
24 hours after
What is the treatment for methotrexate toxicity?
Folinic acid
How long should a patient stop taking methotrexate for before trying to conceive?
6 months
What is the treatment for Paget’s disease of the bone?
Bisphosphonates
What is the treatment for Raynaud’s?
Nifedipine (CCB)
What is the most prominent side effect of bisphosphonates?
Oesophageal problems
What is the drug treatment for osteomalacia?
Vitamin D supplementation
What is the management of patients who suffer bad GI side effects from alendronate?
Change to risedronate
What drugs can cause drug induced lupus?
hydralazine (most common)
isoniazid, penicillamine, procainamide, phenytoin