pharmacokinetics terms Flashcards

1
Q

bioavailability

A

Degree to which a drug is absorbed and reaches the general circulation

A ‘Margin of Safety’
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2
Q

Half life

A

Time required to reduce the total amount of a drug in a person’s body by 50%

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3
Q

Therapeutic index

A

Relationship between a drug’s therapeutic effect and adverse effects

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4
Q

Polypharmacy

A

Refers to the use of multiple medication by a patient (usually 5 or more drugs simultaneously)

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5
Q

Why is polypharmacy good and bad

A

Good:
* Manages multiple health problems

Bad:
* Drug interaction -interaction with other drugs may lead to reduced effectiveness or harmful side effects
* Adverse side effects- multiple drugs=increase toxicity and side effects

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6
Q

De-prescribing

A

is the process of tapering, stopping, discontinuing, or withdrawing drugs, with the goal of managing polypharmacy and improving outcomes”

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