pharmacokinetics terms Flashcards
bioavailability
Degree to which a drug is absorbed and reaches the general circulation
A ‘Margin of Safety’
Look at ppt
Half life
Time required to reduce the total amount of a drug in a person’s body by 50%
Therapeutic index
Relationship between a drug’s therapeutic effect and adverse effects
Polypharmacy
Refers to the use of multiple medication by a patient (usually 5 or more drugs simultaneously)
Why is polypharmacy good and bad
Good:
* Manages multiple health problems
Bad:
* Drug interaction -interaction with other drugs may lead to reduced effectiveness or harmful side effects
* Adverse side effects- multiple drugs=increase toxicity and side effects
De-prescribing
is the process of tapering, stopping, discontinuing, or withdrawing drugs, with the goal of managing polypharmacy and improving outcomes”