Pharmacokinetics Flashcards
1
Q
Distribution
A
Pharmacokinetic data on extent and nature of distribution, including volume of distribution (Vd) and the extent of protein binding, are provided.
2
Q
Metabolism
A
Pharmacokinetic data on metabolic pathways, including cytochrome P450 pathway of elimination, and whether a drug is an enzyme inducer or inhibitor, are provided.
3
Q
Elimination
A
Pharmacokinetic data on extent of renal (or other) elimination, as well as elimination half-life, are provided.
4
Q
Absorption
A
Pharmacokinetic parameters related to oral bioavailability (F) and the impact of food on absorption are provided.