Pharmacokinetics

Question 1

Define absorption (of a drug)

Answer 1

transportation of the unmetabolised drug from the site of administration to the body circulation system

Question 2

Define enteral absorption

Answer 2

Enteral absorption is drug that is metabolised via the human gut (as in oral medication)

Question 3

Define parenteral absorption

Answer 3

Not absorbed via the gut/alimentary tract e.g. IV, SC, IM etc

Question 4

Define Distribution

Answer 4

The reversible movement of drug between body compartments once it has entered the systemic circulation

Question 5

Define volume of distribution

Answer 5

the amount of drug in the body compared with concentration of the drug in the blood plasma. This predicts whether the drug will largely collect in the blood or in the tissue. Drugs that remain within the vascular system will have a low volume of distribution, while drugs that are highly bound to tissue will have a high volume of distribution