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Pharm > Pharmacogenetics > Flashcards

Pharmacogenetics Flashcards

1
Q

Abacavir (Ziagen)

A

Anti-retro viral
Genetic pre screening mandatory
SJS can result if pts have HLA variations

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2
Q

Carbamazepine (Tegretol)

A

Mood stabilizer, anti-convulsant
Genetic pre screening mandatory
SJS can result if pts have HLA variations

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3
Q

Clopidogrel (Plavix)

A

Anti-platelet

Prodrug activated by CYP2C19

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4
Q

Codeine

A

Pain
Prodrug activated by CYP2D6
Poor and rapid metabolizers

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5
Q

Imatinib (Gleevec)

A

Oncology

Tyrosine kinase inhibitor

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6
Q

Ivacaftor (kalydeco)

A

Cystic fibrosis

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7
Q

Valporic acid (Depekene)

A

Anti convulsant

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8
Q

Warfarin (Coumadin)

A

Anticoagulation
Inhibits vitamin K epoxide reductase (VKOR)
3 dosing sensitivities
Metabolized by CYP2C9

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Pharm (5 decks)

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