pharmacoepidemiology

Question 1

define pharmacoepidemiology

Answer 1

the application of epidemiologic knowledge, methods and reasoning to the study of the effects and uses of drugs in human populations

Question 2

14 children died of tetanus in 1901

Answer 2

biologics control act of 1902

Question 3

100 died due to ethylene glycol in elixir of sulfanilamide in 1936

Answer 3

federal FD&C act of 1938

Question 4

cutter incident, several children contract polio and/or die from Salk vaccine in 1955

Answer 4

division of biological standards created

Question 5

thalidomide causes severe birth defects in thousands of babies in western Europe in 1962

Answer 5

Kefauver-Harris drug amendments of 1962

Question 6

cyanide poisoning via Tylenol capsules in 1982

Answer 6

federal anti-tampering act of 1983

Question 7

Factors of drug-related morbidity and mortality

Answer 7

1. untreated indication
2. improper drug
3. subtherapeutic dose
4. failure to receive drug
5. over dosage
6. ADR
7. drug-drug interaction
8. drug use w/o indication

Question 8

does prescription drug use increase or decrease with age

Answer 8

increase

Question 9

who is more likely to use drugs, men or women?

Answer 9

women

Question 10

race with highest prescription use

Answer 10

white population

Question 11

race with lowest prescription use

Answer 11

Mexican-American

Question 12

percentage Medicare paid for medications in 2004

Answer 12

2%

Question 13

percentage Medicare paid for medications in 2014

Answer 13

29%