Pharmacodynamics Flashcards
What is pharmacokinetics the movement of
Drugs in the body
Pharmacokinetics is the process by which drugs are
Absorbed, distributed, metabolized and excreted over time
Pharmacodynamics is represented when the drug and/or substance is
Already in the body
Pharmacodynamics is when the contact happens with the tissues…
What is the impact on the tissues, what are the effects
What are the 3 factors that influence the effects of a drug on the body and behavior
1) Drug site of action
2) Affinity
3) Efficacy
The 3 factors that influence the effects of a drug on the body and behavior represents what (Pharmacodynamics or pharmacokinetics)
Pharmacodynamics
What is important to note about efficacy and affinity
They are independent of each other
What is a drugs affinity
How strong a drug binds to a receptor
With a drug that has high affinity do you need a low or high concentration of that drug to bind to many receptors
Low
What is efficacy
How strongly a drug ACTIVATES a receptor, once the binding already happened
Antagonist drugs have ___________ efficacy
low
Agonist drugs have ___________ efficacy
High
What drug is known as a full agonist
Morphine
What is a full agonist drug
Rapid binding and activation
What is an antagonist drug that inhibits other drugs from binding
Naloxone
What is important to note about the bindings of drugs
It is TEMPORARY, AFTER SOME TIME THE DRUG WILL UNBIND FROM THE RECEPTOR
What is the duration of binding of a drug influenced by
Drugs affinity and others
True or false receptors have a limited life span
True
