Pharmacodynamics Flashcards
1
Q
What is meant by
affinity?
A
How well a drug binds to a chemically sensitive receptor.
2
Q
What is meant by specifity?
A
Ability of a drug to combine with a particular receptor.
3
Q
What is meant by potency?
A
Amount of drug required to produce a response.
4
Q
Antagonists can be…..
A
Competitive or non-competitive. Most are competitive.
5
Q
What is meant by efficacy?
A
How well an agonist achieves a response.
6
Q
What is a partial agonist?
A
A drug that produces a less than maximal response = lower efficacy.
7
Q
What is tolerance caused by?
A
Desensitisation of receptors from repeated use. Can also cause a reduction in the amount of receptors.
8
Q
Enzyme inhibition can be:
A
Competitive
Non-Competitive
Reversible
Irreversible
