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Mocks > Pharmaco > Flashcards

Pharmaco Flashcards

1
Q

Which antibiotics cannot be given concurrently with tetracycline?

A

Penicillin

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2
Q

Drug of choice for treating herpes

A

Acyclovir

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3
Q

What are sulfonamides? How do they work?

A

Bateriostatic inhibitor of folic acid
Mainly intereferes with bacterial PABA

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4
Q

Which group of antibiotics have additional anti-inflammatory and immunomodulatory functions?

A

Macrolides

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5
Q

Which medicament use can produce verrill’s sign?

A

Diazepam

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6
Q

Which drug is used in first line emergency treatment of epilepsy?

A

Diazepam

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7
Q

What is therapeutic index of drug indicative of?

A

Drug safety

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8
Q

Mechanism of action of Nitroglycerin

A

Direct action on smooth muscle

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9
Q

Why is Mg and Al added to antacids?

A

Mg causes diarrhoea
Al causes constipation

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10
Q

What is Omeprazole

A

Proton pump inhibitor

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11
Q

Example of short-acting and long-acting beta 2 agonist

A

Short: Salbutamol
Long: Salmeterol

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12
Q

Which group of antihypertensives are contraindicated during pregnancy?

A

ACE inhibitors

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13
Q

What is furosemide? Indication

A

Thiazide: Oral diuretic
Used in pulmonary edema

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14
Q

What does inter-dose interval depend on?

A

Half-life of drug

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15
Q

Which type of hypersensitivity can be induced from penicillin?

A

Type B

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16
Q

Best measuring index for cardiovascular disease

A

LDL/HDL Ratio

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17
Q

Myocardial infarct biomarker

A

CPK-MB

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18
Q

Most common long-term side effect of carbamazepine

A

Aplastic anemia

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19
Q

Heparin antagonist

A

Protamine sulphate

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20
Q

Drug used in neuropathic pain

A

Gabapentin

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21
Q

Drug of choice for chronic gout patient with renal impairment

A

Allopurinol

22
Q

Which group of antihypertensives lack vasodilatatory property?

A

Beta Blockers

23
Q

Which new gen sialogogue has additional M3 action?

A

Cemiveline

24
Q

Mechanism of action of atorvastatin

A

Competitive inhibition of HMG CoA reductase - REDUCES LDL

25
Q

Raloxifen is drug of choice for

A

Osteoporosis in post-menopausal women

26
Q

Hemophilia is treated with which drug to release factor VIII?

A

Vasopressin/Desmopressin

27
Q

Role of Beta Blocker in angina?

A

Decrease the work load of heart

28
Q

What should isioniazid be supplemented with?

A

Pyridoxine

29
Q

Drug of choice for VRSA

A

Linezolid

30
Q

Anaesthetic with antiemetic property

A

Propofol

31
Q

Advantage of penicillin V over penicillin G

A

Better oral absorption

32
Q

Mechanism of action of chloramphenicol

A

Protein synthesis inhibition

33
Q

Penicillinase resistant penicillin

A

Cloxacillin

34
Q

Metronidazole mechanism of action

A

DNA target

35
Q

First line tubercular drugs

A

Isoniazid
Rifampicin
Ethambutol

36
Q

Which AB cause ear damage?

A

Aminoglycosides

37
Q

Which drug is used to reverse respiratory depression caused by benzos?

A

Flumazenil

38
Q

Main disadvantage of opioid disadvantage

A

Urinary retention

39
Q

Antihypertensives used in diabetics

A

ATI (Losartan)
ACE Inhibitor (Enalapril)

40
Q

What is digitalis used for?

A

Heart failure

41
Q

Which drug causes orange discoloration of sweat?

A

Rifampicin

42
Q

Through which process is drug resistance transferred?

A

Conjugation

43
Q

First line drug for TB

A

Isoniazid

44
Q

Topical agent used for oral thrush

A

Clotrimazole

45
Q

AB which possess additional anti-inflammatory and immunomodulatory activities

A

Macrolides

46
Q

Which AB is most frequently associated with pseudomembranous colitis

A

Clindamycin

47
Q

Penicillin with best gram negative spectrum?

A

Ampicillin

48
Q

Chloramphenicol mechanism of action

A

Protein (50s)

49
Q

Which 2 groups of medications reduce anticoagulant action?

A

Barbiturates
Oral contraceptives

50
Q

Grand mal epilepsy patients are treated with which durg?

A

Phenytoin

Mocks (4 decks)

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