Pharmaco Flashcards

1
Q

Which antibiotics cannot be given concurrently with tetracycline?

A

Penicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drug of choice for treating herpes

A

Acyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are sulfonamides? How do they work?

A

Bateriostatic inhibitor of folic acid
Mainly intereferes with bacterial PABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which group of antibiotics have additional anti-inflammatory and immunomodulatory functions?

A

Macrolides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which medicament use can produce verrill’s sign?

A

Diazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which drug is used in first line emergency treatment of epilepsy?

A

Diazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is therapeutic index of drug indicative of?

A

Drug safety

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Mechanism of action of Nitroglycerin

A

Direct action on smooth muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why is Mg and Al added to antacids?

A

Mg causes diarrhoea
Al causes constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is Omeprazole

A

Proton pump inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Example of short-acting and long-acting beta 2 agonist

A

Short: Salbutamol
Long: Salmeterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which group of antihypertensives are contraindicated during pregnancy?

A

ACE inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is furosemide? Indication

A

Thiazide: Oral diuretic
Used in pulmonary edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does inter-dose interval depend on?

A

Half-life of drug

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which type of hypersensitivity can be induced from penicillin?

A

Type B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Best measuring index for cardiovascular disease

A

LDL/HDL Ratio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Myocardial infarct biomarker

A

CPK-MB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Most common long-term side effect of carbamazepine

A

Aplastic anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Heparin antagonist

A

Protamine sulphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Drug used in neuropathic pain

A

Gabapentin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Drug of choice for chronic gout patient with renal impairment

A

Allopurinol

22
Q

Which group of antihypertensives lack vasodilatatory property?

A

Beta Blockers

23
Q

Which new gen sialogogue has additional M3 action?

A

Cemiveline

24
Q

Mechanism of action of atorvastatin

A

Competitive inhibition of HMG CoA reductase - REDUCES LDL

25
Raloxifen is drug of choice for
Osteoporosis in post-menopausal women
26
Hemophilia is treated with which drug to release factor VIII?
Vasopressin/Desmopressin
27
Role of Beta Blocker in angina?
Decrease the work load of heart
28
What should isioniazid be supplemented with?
Pyridoxine
29
Drug of choice for VRSA
Linezolid
30
Anaesthetic with antiemetic property
Propofol
31
Advantage of penicillin V over penicillin G
Better oral absorption
32
Mechanism of action of chloramphenicol
Protein synthesis inhibition
33
Penicillinase resistant penicillin
Cloxacillin
34
Metronidazole mechanism of action
DNA target
35
First line tubercular drugs
Isoniazid Rifampicin Ethambutol
36
Which AB cause ear damage?
Aminoglycosides
37
Which drug is used to reverse respiratory depression caused by benzos?
Flumazenil
38
Main disadvantage of opioid disadvantage
Urinary retention
39
Antihypertensives used in diabetics
ATI (Losartan) ACE Inhibitor (Enalapril)
40
What is digitalis used for?
Heart failure
41
Which drug causes orange discoloration of sweat?
Rifampicin
42
Through which process is drug resistance transferred?
Conjugation
43
First line drug for TB
Isoniazid
44
Topical agent used for oral thrush
Clotrimazole
45
AB which possess additional anti-inflammatory and immunomodulatory activities
Macrolides
46
Which AB is most frequently associated with pseudomembranous colitis
Clindamycin
47
Penicillin with best gram negative spectrum?
Ampicillin
48
Chloramphenicol mechanism of action
Protein (50s)
49
Which 2 groups of medications reduce anticoagulant action?
Barbiturates Oral contraceptives
50
Grand mal epilepsy patients are treated with which durg?
Phenytoin