Pharmaceutics Exam 101 Flashcards
In getting a prescription what should be evaluated
Patient, Drug
What does BUD mean
Beyond use date
What are the three comprenhisive pharmaceutics book
Remingtons, Merck index, Trissels
Lidocaine is not soluble in water
True
What is the difference between Category 1 and Category 2
Category 1 can be compounded in an unclassified segregated compounding area (SCA), Category 2 must be prepared in a cleanroom suite (buffer room with ante room)
What is the max BUD in controlled room temperature for Category 1 products, refrigerated BUD
less than 12 hours, less than 24 hours
T/F: If the manufacturer has shorter BUDs it is best to go with those
True
What is the BUD of solids (capsules, tablets, granules, powders), how does it need to be stored
180 days, controlled room temp
What is the BUD of preserved aqueous (suspensions emulsions, gels, creams, lotions, solutions, sprays), how does it need to be stored
30 days, controlled room temp
What is the bud of non-preserved Aqueous (suspensions, emulsions, gels, creams, lotions, solutions sprays), how does it need to be stored
14, refrigerator
What is the BUD of Non-Aqeous (suppositories, ointments), how does it need to be stored
90, controlled room temp
T/F: USP 795 is for non-sterile, USP/ USP 797 is for non harzardous sterile, and USP 800 is for harzardous sterile
True
T/F: Commercial pharmacy is usually 18 months and starts from where production starts and can include the months in factory before given to the pharmacy
True
What do all drugs have
API, excipients, packaging, administration device
When using a commercial product what type of release should be used
Immediate release
What is the purpose of having adsorbent excipients, what is the most common example
Keep powers dry, Magnesium Oxide
What is the purpose of having antioxidant excipients, what is the most common example
prevents oxidation, Ascorbic acid
What is the purpose of having binder excipients
Adhesive materials hold powders together
What is the purpose of having coating excipients, what are the most common examples
Prevent degradation due to oxygen, light, moisture, mask bad taste/ shellack, gelatin
What is the purpose of having diluent excipients, what are the most common examples
add size to very small dosages/Starches, calcium salts, lactose, cellulose
What is the purpose of disintegrant excipients
Causes tablet to swell and burst
What is the purpose of enteric coating excipients
Protective layer to prevent dissolution in the stomach
What are the most common flavoring agents, sweetner
Saccharin, mannitol, sorbitol
What is the purpose for humectant excipients
Prevents preparations from becoming brittle
