Pharmaceutics Exam 101 Flashcards

1
Q

In getting a prescription what should be evaluated

A

Patient, Drug

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2
Q

What does BUD mean

A

Beyond use date

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3
Q

What are the three comprenhisive pharmaceutics book

A

Remingtons, Merck index, Trissels

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4
Q

Lidocaine is not soluble in water

A

True

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5
Q

What is the difference between Category 1 and Category 2

A

Category 1 can be compounded in an unclassified segregated compounding area (SCA), Category 2 must be prepared in a cleanroom suite (buffer room with ante room)

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6
Q

What is the max BUD in controlled room temperature for Category 1 products, refrigerated BUD

A

less than 12 hours, less than 24 hours

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7
Q

T/F: If the manufacturer has shorter BUDs it is best to go with those

A

True

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8
Q

What is the BUD of solids (capsules, tablets, granules, powders), how does it need to be stored

A

180 days, controlled room temp

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9
Q

What is the BUD of preserved aqueous (suspensions emulsions, gels, creams, lotions, solutions, sprays), how does it need to be stored

A

30 days, controlled room temp

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10
Q

What is the bud of non-preserved Aqueous (suspensions, emulsions, gels, creams, lotions, solutions sprays), how does it need to be stored

A

14, refrigerator

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11
Q

What is the BUD of Non-Aqeous (suppositories, ointments), how does it need to be stored

A

90, controlled room temp

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12
Q

T/F: USP 795 is for non-sterile, USP/ USP 797 is for non harzardous sterile, and USP 800 is for harzardous sterile

A

True

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13
Q

T/F: Commercial pharmacy is usually 18 months and starts from where production starts and can include the months in factory before given to the pharmacy

A

True

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14
Q

What do all drugs have

A

API, excipients, packaging, administration device

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15
Q

When using a commercial product what type of release should be used

A

Immediate release

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16
Q

What is the purpose of having adsorbent excipients, what is the most common example

A

Keep powers dry, Magnesium Oxide

17
Q

What is the purpose of having antioxidant excipients, what is the most common example

A

prevents oxidation, Ascorbic acid

18
Q

What is the purpose of having binder excipients

A

Adhesive materials hold powders together

19
Q

What is the purpose of having coating excipients, what are the most common examples

A

Prevent degradation due to oxygen, light, moisture, mask bad taste/ shellack, gelatin

20
Q

What is the purpose of having diluent excipients, what are the most common examples

A

add size to very small dosages/Starches, calcium salts, lactose, cellulose

21
Q

What is the purpose of disintegrant excipients

A

Causes tablet to swell and burst

22
Q

What is the purpose of enteric coating excipients

A

Protective layer to prevent dissolution in the stomach

23
Q

What are the most common flavoring agents, sweetner

A

Saccharin, mannitol, sorbitol

24
Q

What is the purpose for humectant excipients

A

Prevents preparations from becoming brittle

25
Q

What is the purpose of lubricant excipients, what are the most common examples

A

Helps keep ingredients from sticking to each other and to the equipment, magnesium stearate

26
Q

What is the purpose of preservatives, what are the most common examples

A

Prevent growth of bacteria and other pathogens/ sodium benzoate, benzoic acid, benzalkonium chloride

27
Q

What is the purpose of mortar and pestle

A

particle size reduction of hard solids

28
Q

T/F: If receiving leftover drug from a mortar and pestle it should be scraped out with a rubber spatula

A

True

29
Q

Which particle size reduction is dry, wet

A

Triturgation, levigation

30
Q

T/F: The smaller the capsule the larger it holds

A

True

31
Q

What is the proper mortal and pestle that should be used

A

Glass