Pharmaceuticals Flashcards
What are the 5 most common side effects from RT and when do they occur?
- nausea (hours after)
- diarrhoea (7-14 days)
- skin reaction (7-14 days)
- mucositis (7-14 days)
- oesophagitis (7-14 days)
What is the medication for nausea?
- zofran
What is the medication for diarrhoea?
- gastro-stop
What is the medication for skin reaction?
- skin lotion
- aqueous cream
- aloe vera (pure)
- Moo goo
- hydrocortisone (1%)
What is the medication for mucositis?
- opioids
What is the meidcation for oesophagitis?
- mylanta
What medication is given to patient recieving whole brain?
- dexamethasone
- purpose is to reduce swelling in brain
What medication is given to patient recieveing GIT RT?
- loperamide/immodium
What are the four types of chemo drugs?
- alkylating agent (nitrogen mustards)
- cisplatin and its analogues (cisplatin)
- antimetabolites (vincristine)
- anti-microtubules agents (5-FU)
What are the two chemos you cant have concunerntly with RT?
- pemetrexed
- gemcitabane
What are the types of chemo and RT sequencing?
- adjuvant (after)
- concurrent (with, within an hour before)
- neoadjuvant (before)
- sandwich
What is difference between chemo and targeted therapy?
Chemo:
- acts on all rapidly diving cells
- cytotoxic (kills tumour cells)
Targeted:
- acts on specific molecular targets that is associated with cancer
- cytostatic (blocks tumour cells proliferation)
What is a common hormonal treatment?
- zoledex
- lucrin (prostate)
- tamoxifen (breast)
Generally how do targeted drugs work?
- block chemical signals
- change proteins
- stop making new blood vessels
- trigger your immune system to kill cancer cells
- carry a toxin to cancer cells
What is an example of a MAB?
- cetuximab
- Ipilimumab (melanoma)
