Pharma Midterm 2 Flashcards

1
Q

SHort acting insulin ? peaks in 20 min and reg. in 2 hrs

A

lispro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

intermediate lasting insulin? peaks in 6 hrs

A

Neutral protamine hagedorn (NPH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Long lasting insulin? only used in hospitals

A

glargine & detemir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

anxiolytic drug that is used in the hospitals

A

benzodiazepine (valium)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drug that allows the pt to go into delta sleep waves

A

zolpidim (ambien)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

name the four SSRIs

A
  1. paxil
  2. desyrel
  3. zoloft
  4. prozac
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

barbiturates target ___ receptors

A

GABA receptors and open Cl- channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

GABA receptor drug that is used for anticonvulsions

A

barbiturates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What enzyme does ethanol target

A

aldehyde dehydrogenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Non-barbiturate that is used for sedation and hypnotic. Allows the pt to sleep 1-6 hrs

A

Chloral Hydrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What type of hallucinations can be a side effect of chloral hydrate? (Non- barbiturate)

A

auditory hallucination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

iontropic and chronotropic drug that works on the heart and is used for asthma

A

methylaxanthine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

drug that stim gg

A

nicotine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

drug used as a local anesthetic

A

cocaine

fxn: blocks reuptake of NE from gg to neuron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

drug used for ADHD and narcolepsy

A

amphetamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

tx for LSD

A

haloperidol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

THC causes ____ hallucinations

A

visual hallucinations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

drug that causes dissociative anesthesia

A

Phencyclidine (PCP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Hallucinogen drug that inhibits the uptake of NE, serotonin and Dopamine

A

Phencyclidine (PCP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

“-amine”

A

antidepressants:

imipramine and desimipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

imipramine and desimipramine blocks ___ & ___ reuptake

A

NE and seretonin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

drugs used for SEVERE depression

A

imipramine and desimipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

drug used for bed wetting

A

imipramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

3 types of receptors that imipramine and desimipramine inhibit

A

muscarinic
histamine
alpha receptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
PT is suffering from bulimia/ OCD and Nervosa what drug should she take?
SSRI: fluoxetine (prozac)
26
MAOI's active ___ and ___ receptors
NE and Seretonin
27
What drugs can cause HT crisis
MAOI's eat tyramine
28
Phenelizine (Nardil)
MAOI
29
MC drug used for Schizophrenics
risperidone Others: * Clozapine * haloperidol * thiothixene: tx for LSD
30
___ & ___ is used for tx nausea and vomiting
chlorpromazine & scopolamine
31
Side effects of risperidone (drugs for schizo)
parkinsonian | tardive dyskinesia
32
MC side effect of morphine
constipation | others: decr respiratory and vomiting
33
What type of receptor does merperidine (demorol) work on?
kappa
34
name 4 strong opoiods
1. morphine 2. merperidine (demorol) 3. Methadone 4. Heroin
35
Which opoiod mimics morphine and lasts longer? Which opoiod crosses the bl. brain barrier faster than morphine?
last longer: Methadone works faster: Heroin
36
Drug used to tx mprphine and heroin addicts
methadone
37
moderate opoiod that has antitussive activity
codeine
38
What does a person have before a grand mal seizure
tactile skin feeling, aura prodrome
39
all meds for epilepsy inhibit brain cells by binding to ___
GABA
40
epileptic meds cause ____ channels to open and slow down seizures
IPSP
41
MC side effect of anticonvulsant drugs
nystagmus and ataxia
42
MC epileptic med for grand mal
carbamazepine | carb= macro
43
1st choice of med for petit mal
ethosuximide (zerontin)
44
long acting Type I DM med
glargine & detemir
45
DM med that stim insulin release
sulfonylureas 1. tolbutamide 2. glucotrol
46
Dm med that can be used during pregos
glyburide
47
Dm med that inhibits liver glucose production
Biguanides (Metformin)
48
DM med that increases the peripheral insulin sensitivity
Thiozolidinediones (rosiglitazone)
49
When DM meds that can cause MI and anemia
Thiozolitazone = rosiglitazone | increases peripheral insulin sensitivity
50
DM med that can cause VIt B12 GI disturbance
Biguanide (Metformin= glucophage)
51
____: inhibits carbonic anhydrase enzyme ( reduces bicarbonate reabsorption)
Acetazolamide (Diamox) : Carbonic Anhydrase inhibitors
52
side effect of acetazolamide (Diamox)
Metabolic acidosis
53
___: inhibits the CO-transporters of Na, K and Cl
Furosemide (lasix)
54
drug used when someone has HPT
furosemide (lasix) - increased the Ca+ conc of urine
55
emergency rug for acute pulm edema due to CHF
furosemide (lasix)
56
drug used on the distal tubule to incr Na, K, and Cl excretion
hydrochlorothiazide (esidrix)
57
drug that can cause hyperkalemia because it inhibits K secretion and Na reabsorption
spironolactone (aldactone)
58
what NT does propranolol decrease
renin (B - blocker)= decr CO
59
"-nolol"
b- blockers
60
"-pril"
ACE inhibitors
61
"-zosin"
a-1 adrenergic blockers
62
side effect of hydralazine (vasodilator)
lupus like sx
63
side effect of minoxidil (vasodilator)
hypertrichosis (abn. hair growth)
64
emergency HT med that is applied only through IV
sodium Nitroprusside given when BP is over 150mmHg
65
cocaine blocks the reuptake of __
NE