Pharma Midterm 2 Flashcards
SHort acting insulin ? peaks in 20 min and reg. in 2 hrs
lispro
intermediate lasting insulin? peaks in 6 hrs
Neutral protamine hagedorn (NPH)
Long lasting insulin? only used in hospitals
glargine & detemir
anxiolytic drug that is used in the hospitals
benzodiazepine (valium)
Drug that allows the pt to go into delta sleep waves
zolpidim (ambien)
name the four SSRIs
- paxil
- desyrel
- zoloft
- prozac
barbiturates target ___ receptors
GABA receptors and open Cl- channels
GABA receptor drug that is used for anticonvulsions
barbiturates
What enzyme does ethanol target
aldehyde dehydrogenase
Non-barbiturate that is used for sedation and hypnotic. Allows the pt to sleep 1-6 hrs
Chloral Hydrate
What type of hallucinations can be a side effect of chloral hydrate? (Non- barbiturate)
auditory hallucination
iontropic and chronotropic drug that works on the heart and is used for asthma
methylaxanthine
drug that stim gg
nicotine
drug used as a local anesthetic
cocaine
fxn: blocks reuptake of NE from gg to neuron
drug used for ADHD and narcolepsy
amphetamine
tx for LSD
haloperidol
THC causes ____ hallucinations
visual hallucinations
drug that causes dissociative anesthesia
Phencyclidine (PCP)
Hallucinogen drug that inhibits the uptake of NE, serotonin and Dopamine
Phencyclidine (PCP)
“-amine”
antidepressants:
imipramine and desimipramine
imipramine and desimipramine blocks ___ & ___ reuptake
NE and seretonin
drugs used for SEVERE depression
imipramine and desimipramine
drug used for bed wetting
imipramine
3 types of receptors that imipramine and desimipramine inhibit
muscarinic
histamine
alpha receptors
PT is suffering from bulimia/ OCD and Nervosa what drug should she take?
SSRI: fluoxetine (prozac)
MAOI’s active ___ and ___ receptors
NE and Seretonin
What drugs can cause HT crisis
MAOI’s
eat tyramine
Phenelizine (Nardil)
MAOI
MC drug used for Schizophrenics
risperidone
Others:
- Clozapine
- haloperidol
- thiothixene: tx for LSD
___ & ___ is used for tx nausea and vomiting
chlorpromazine & scopolamine
Side effects of risperidone (drugs for schizo)
parkinsonian
tardive dyskinesia
MC side effect of morphine
constipation
others: decr respiratory and vomiting
What type of receptor does merperidine (demorol) work on?
kappa
name 4 strong opoiods
- morphine
- merperidine (demorol)
- Methadone
- Heroin
Which opoiod mimics morphine and lasts longer?
Which opoiod crosses the bl. brain barrier faster than morphine?
last longer: Methadone
works faster: Heroin
Drug used to tx mprphine and heroin addicts
methadone
moderate opoiod that has antitussive activity
codeine
What does a person have before a grand mal seizure
tactile skin feeling, aura prodrome
all meds for epilepsy inhibit brain cells by binding to ___
GABA
epileptic meds cause ____ channels to open and slow down seizures
IPSP
MC side effect of anticonvulsant drugs
nystagmus and ataxia
MC epileptic med for grand mal
carbamazepine
carb= macro
1st choice of med for petit mal
ethosuximide (zerontin)
long acting Type I DM med
glargine & detemir
DM med that stim insulin release
sulfonylureas
- tolbutamide
- glucotrol
Dm med that can be used during pregos
glyburide
Dm med that inhibits liver glucose production
Biguanides (Metformin)
DM med that increases the peripheral insulin sensitivity
Thiozolidinediones (rosiglitazone)
When DM meds that can cause MI and anemia
Thiozolitazone = rosiglitazone
increases peripheral insulin sensitivity
DM med that can cause VIt B12 GI disturbance
Biguanide (Metformin= glucophage)
____: inhibits carbonic anhydrase enzyme ( reduces bicarbonate reabsorption)
Acetazolamide (Diamox) : Carbonic Anhydrase inhibitors
side effect of acetazolamide (Diamox)
Metabolic acidosis
___: inhibits the CO-transporters of Na, K and Cl
Furosemide (lasix)
drug used when someone has HPT
furosemide (lasix)
- increased the Ca+ conc of urine
emergency rug for acute pulm edema due to CHF
furosemide (lasix)
drug used on the distal tubule to incr Na, K, and Cl excretion
hydrochlorothiazide (esidrix)
drug that can cause hyperkalemia because it inhibits K secretion and Na reabsorption
spironolactone (aldactone)
what NT does propranolol decrease
renin
(B - blocker)= decr CO
“-nolol”
b- blockers
“-pril”
ACE inhibitors
“-zosin”
a-1 adrenergic blockers
side effect of hydralazine (vasodilator)
lupus like sx
side effect of minoxidil (vasodilator)
hypertrichosis (abn. hair growth)
emergency HT med that is applied only through IV
sodium Nitroprusside
given when BP is over 150mmHg
cocaine blocks the reuptake of __
NE