Pharma Midterm 2 Flashcards

1
Q

SHort acting insulin ? peaks in 20 min and reg. in 2 hrs

A

lispro

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2
Q

intermediate lasting insulin? peaks in 6 hrs

A

Neutral protamine hagedorn (NPH)

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3
Q

Long lasting insulin? only used in hospitals

A

glargine & detemir

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4
Q

anxiolytic drug that is used in the hospitals

A

benzodiazepine (valium)

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5
Q

Drug that allows the pt to go into delta sleep waves

A

zolpidim (ambien)

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6
Q

name the four SSRIs

A
  1. paxil
  2. desyrel
  3. zoloft
  4. prozac
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7
Q

barbiturates target ___ receptors

A

GABA receptors and open Cl- channels

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8
Q

GABA receptor drug that is used for anticonvulsions

A

barbiturates

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9
Q

What enzyme does ethanol target

A

aldehyde dehydrogenase

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10
Q

Non-barbiturate that is used for sedation and hypnotic. Allows the pt to sleep 1-6 hrs

A

Chloral Hydrate

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11
Q

What type of hallucinations can be a side effect of chloral hydrate? (Non- barbiturate)

A

auditory hallucination

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12
Q

iontropic and chronotropic drug that works on the heart and is used for asthma

A

methylaxanthine

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13
Q

drug that stim gg

A

nicotine

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14
Q

drug used as a local anesthetic

A

cocaine

fxn: blocks reuptake of NE from gg to neuron

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15
Q

drug used for ADHD and narcolepsy

A

amphetamine

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16
Q

tx for LSD

A

haloperidol

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17
Q

THC causes ____ hallucinations

A

visual hallucinations

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18
Q

drug that causes dissociative anesthesia

A

Phencyclidine (PCP)

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19
Q

Hallucinogen drug that inhibits the uptake of NE, serotonin and Dopamine

A

Phencyclidine (PCP)

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20
Q

“-amine”

A

antidepressants:

imipramine and desimipramine

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21
Q

imipramine and desimipramine blocks ___ & ___ reuptake

A

NE and seretonin

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22
Q

drugs used for SEVERE depression

A

imipramine and desimipramine

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23
Q

drug used for bed wetting

A

imipramine

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24
Q

3 types of receptors that imipramine and desimipramine inhibit

A

muscarinic
histamine
alpha receptors

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25
Q

PT is suffering from bulimia/ OCD and Nervosa what drug should she take?

A

SSRI: fluoxetine (prozac)

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26
Q

MAOI’s active ___ and ___ receptors

A

NE and Seretonin

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27
Q

What drugs can cause HT crisis

A

MAOI’s

eat tyramine

28
Q

Phenelizine (Nardil)

A

MAOI

29
Q

MC drug used for Schizophrenics

A

risperidone

Others:

  • Clozapine
  • haloperidol
  • thiothixene: tx for LSD
30
Q

___ & ___ is used for tx nausea and vomiting

A

chlorpromazine & scopolamine

31
Q

Side effects of risperidone (drugs for schizo)

A

parkinsonian

tardive dyskinesia

32
Q

MC side effect of morphine

A

constipation

others: decr respiratory and vomiting

33
Q

What type of receptor does merperidine (demorol) work on?

A

kappa

34
Q

name 4 strong opoiods

A
  1. morphine
  2. merperidine (demorol)
  3. Methadone
  4. Heroin
35
Q

Which opoiod mimics morphine and lasts longer?

Which opoiod crosses the bl. brain barrier faster than morphine?

A

last longer: Methadone

works faster: Heroin

36
Q

Drug used to tx mprphine and heroin addicts

A

methadone

37
Q

moderate opoiod that has antitussive activity

A

codeine

38
Q

What does a person have before a grand mal seizure

A

tactile skin feeling, aura prodrome

39
Q

all meds for epilepsy inhibit brain cells by binding to ___

A

GABA

40
Q

epileptic meds cause ____ channels to open and slow down seizures

A

IPSP

41
Q

MC side effect of anticonvulsant drugs

A

nystagmus and ataxia

42
Q

MC epileptic med for grand mal

A

carbamazepine

carb= macro

43
Q

1st choice of med for petit mal

A

ethosuximide (zerontin)

44
Q

long acting Type I DM med

A

glargine & detemir

45
Q

DM med that stim insulin release

A

sulfonylureas

  1. tolbutamide
  2. glucotrol
46
Q

Dm med that can be used during pregos

A

glyburide

47
Q

Dm med that inhibits liver glucose production

A

Biguanides (Metformin)

48
Q

DM med that increases the peripheral insulin sensitivity

A

Thiozolidinediones (rosiglitazone)

49
Q

When DM meds that can cause MI and anemia

A

Thiozolitazone = rosiglitazone

increases peripheral insulin sensitivity

50
Q

DM med that can cause VIt B12 GI disturbance

A

Biguanide (Metformin= glucophage)

51
Q

____: inhibits carbonic anhydrase enzyme ( reduces bicarbonate reabsorption)

A

Acetazolamide (Diamox) : Carbonic Anhydrase inhibitors

52
Q

side effect of acetazolamide (Diamox)

A

Metabolic acidosis

53
Q

___: inhibits the CO-transporters of Na, K and Cl

A

Furosemide (lasix)

54
Q

drug used when someone has HPT

A

furosemide (lasix)

  • increased the Ca+ conc of urine
55
Q

emergency rug for acute pulm edema due to CHF

A

furosemide (lasix)

56
Q

drug used on the distal tubule to incr Na, K, and Cl excretion

A

hydrochlorothiazide (esidrix)

57
Q

drug that can cause hyperkalemia because it inhibits K secretion and Na reabsorption

A

spironolactone (aldactone)

58
Q

what NT does propranolol decrease

A

renin

(B - blocker)= decr CO

59
Q

“-nolol”

A

b- blockers

60
Q

“-pril”

A

ACE inhibitors

61
Q

“-zosin”

A

a-1 adrenergic blockers

62
Q

side effect of hydralazine (vasodilator)

A

lupus like sx

63
Q

side effect of minoxidil (vasodilator)

A

hypertrichosis (abn. hair growth)

64
Q

emergency HT med that is applied only through IV

A

sodium Nitroprusside

given when BP is over 150mmHg

65
Q

cocaine blocks the reuptake of __

A

NE