Pharma MCQ NATA TEST Flashcards
What is the physical state of a dispersed phase in a suspension ?
A. Solid
B. Liquid
C. Both
D. None of them
A. Solid
Which of the following is characteristic of pastes?
A. Each of these
B. High lipid content
C. High dry material
D. High Water content
C. High Dry material
The EV admin of this anaesthetic drug causes strong tissue irritation?
A.Pentobarbitol
B. Ketamine
C. TileTamine
D. Antipamezole
C. Tiletamine also Imidazoles causes!
Its analgesic activity is negligible ?
A. Xylazine
B. Ketamine
C. Buprenorphine
D. Thiopental
D. Thiopental (used for induction anaesthesia for short procedures)
What is the goal of pharma investigations in drug research?
A. Determination of mechanism of effect
B. Repeated dose toxicity
C. Bioequivalence studies
D. Target animal tolerance
A. Determination of mechanism of effect
Which investigation belongs to the clinical phase?
A. Food safety
B. Field trial
C. Pharmacological study
D. Environmental toxicity
B. Field trials (used on diff. groups of sick animals/ stages of illness)
This ultrashort barb. can be readmin. in one day? A. Pentobarbitol B. Thiamilal C. Methohexital D. Thiopental
C. Methohexital
Which vehicle is a useful preparation for eye ointment?
A. simple ointment
C. Cocoa butter
C. Paraffin
D. White vaseline
D. White vaseline
This type of gen. ana has a pronounced analgesic effect ?
A. Inhalation anaesthetic
B. Ultra short acting barbs
C. Steroid anasthetics
D. Dissociate anaesthetics
D. Dissociate anaesthetics (ketamine, tiletamine)
NONE Of the others have Analg.
Alpha 2 agonist not used in horses?
A. Medetomidine
B. ROMIFIDINE
C. Detomidine
D. Xylazine
A. Medetomidine (for Car, effects like xylazine)
HORSE uses Detomidine !
Which alpha 2 agonist is useful in swine ?
A. Medetomidine
B.Detomidine
C. None of them
D. Both
C. None of them
In the course of registration of licensed EUDRALEX medicines which safety documentation?
A. part 4
B. Part 3
C. Part 2
D. Part 1
C. Part 3
Which is the formulation type of Cremor Auqaporous?
A. Solution
B. O:W emulsion
C. W:O emulsion cream
D. Suspension type
B. O:W with separate lipid and separate solid phase O:W emulsifier: sodium lauryl sulphate Purified water Glycerol and lipid emulsifier Cetosteryalcohol
What matrices are investigated in a P.kinetic exam?
A. Urine
B. Edible tissue
C. Blood
D. Blod, Urine, faeces, Milk, egg
D. Blood, urine, Faeces, milk, egg
Edible tissue is examined in the residue study
Which parameter has to be determined in an acute oral toxicity study ?
A. GHS class - Global Harmonized classification
B. TD 50
C. ED 50
D. Bioequivalence
A. GHS class possible TD 50 but not mentioned in class notes!
Which of the following is a water soluble base?
A.Soft parrafin
B. Hydroxyaethylcellulose
C. Cocoa butter
D. Vaseline
B. HYDROXYAETHYLCELLULOSE
Which of the following is not true?
A. Local tolerance study examines alterations at site of exposure
B. Tetragenic studies examine abnormalities of the embryo
C. Mutagenic examines structural and numerical changes of the chromosomes
D. Pharmacological examines movement of the drug within the body
D. Pharmacological examines the main mechanisms of effect MECHANISM OF ACTIOn (effect on organ system)
The DOA of propofol in dogs is?
A. 15-20 mins
B. 20- 45 mins
C. 20 -30 mins
D. 5- 8 mins
A. 15- 20 mins (Fe up to 30 mins)
ONLY GIVEN IV!
sensitive to microbial infection!
If the aim of these investigations is to determine the accelerated stability of the
product what are the appropriate conditions?
A. Room temp 0-3 months
B. Room temp 0- 4 weeks
C. 40 Degrees C 75 % RH 0-6 months
D. Room temp 0-24 hours
C. 40 C 75 % RH 0-6 months
Which is emulsifying agent?
A. Coca Butter
B. Purified water
C. Preservatives
D. Polysorbate 20
B. Purified water
Polysorbate is a synthetic water soluble ointment
This general anaesthetic drug can cause dose dependent reversible respiratory inhibition ? A. Aflaxon B. Etomidate C. Ketamine D. Thiamilal
D. Thiamilal (accumulate in the fat no readmin!) 5-8 min duration
Antidote for xylazine and medetomidine? A. Anitipameole B.Samazenile C.Fluanisone D. Fluamazenile
A. ANTIPAM = alpha 2 antidote to wake up!
Which drug is a coherent colloid? A.Ointment B. cream C. Gel D. Paste
C. GEL
Others = heterogenous coherent!
What is a major side effect of inhalation aesthetics?
ISOF- local irritation, bronchospasm
no isoflourane for induction!
