Pharma Flashcards
CYP450 inducers
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Barbiturates St. John's wort Carbamazepine Rifampin Alcohol (chronic) Phenytoin Griseofulvin Phenobarbital Sulfonylureas
CYP450 inhibitors
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Valproate Verapamil Isoniazid Cimetidine Ketoconazole Sulfonamides Fluconazole Fluvoxamine Alcohol (acute) Ciprofloxacin (fluoroquinolones) Chloramphenicol Erythromycin (macrolides) Amiodarone (2C9) Omeprazole Grapefruit juice Quinidine
Drugs can given through ETT
N
NAVEL
Nalaxone Atropine Vasopressin Epi Lidocaine
Mnemonic for k sparing medications ‘’The K+ STAys”
Spironolactone,
Triamterene,
Amiloride.
To remember which CYP is most involved with codeine: “coDeine”
The CYP 2D6 enzyme pathway is responsible for the metabolism of codeine to morphine, its active metabolite. Individuals with poor activity of this enzyme pathway are likely to experience treatment failure with codeine therapy.
TrueLearn Insight : Mnemonic for 2D6 and codeine: coDeine has 2 letters, followed by a “D”, then 4 more letters (2 + 4 = 6).
To differentiate GABAA from GABAB, remember
Baclofen for GABAB and Anesthetics for GABAA.
Drugs that typically follow zero-order kinetics are THE PAW:
theophylline, heparin, ethanol, phenytoin, aspirin, warfarin.
A mnemonic to recall the beta-1 selective beta-blockers is “BEAM”
(β1, bisoprolol, betaxolol, esmolol, atenolol, acebutolol, metoprolol).
from A-M -> B1 selective (except Labetalol “nonselective B” & Carvedilol “nonselective B & A1 selective blocker”
