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Pharma Endo > Pharma 5 > Flashcards

Pharma 5 Flashcards

1
Q

⬆️ neutrophil migration and phagocytosis
⬇️ thymocytes and lymphocytes mass

A

Cortisol & cortisol analogue ( prednisolone )

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2
Q

Fludocortisol

A

Highest anti-inflammatory activity
Highest mineralocorticoid activity

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3
Q

Glucocorticoid inhibitor , inhibit 11B hydroxylase

A

Metyrapone

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4
Q

Inhibit desmolase and treat breast cancer

A

Aminoglutethimide

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5
Q

Inhibit first and last step of glucocorticoid synthesis and treat Cushing syndrome

A

Ketoconazole

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6
Q

Blocks glucocorticoid receptor and treat Cushing syndrome

A

Mifepristone

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7
Q

Replacement therapy for Addison disease ( primary)

A

Cortisol & flurocortisol

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8
Q

Replacement therapy of adrenal insufficiency (secondary)

A

Cortisol or prednisolone

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9
Q

Replacement therapy of CAH

A

Mineralocorticoid & glucocorticoid

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10
Q

Withdrawal of glucocorticoid result in :
Hypernatremia
Hyperkalemia
Hyponatremia
Hypokalemia

A

Hyponatremia

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Pharma Endo (5 decks)

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