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BD MD > Pharma > Flashcards

Pharma Flashcards

1
Q

Anti pseudomonal

A

Penicillins- piptaz, ticarcillin
Carbapenem- meropenem, imipenem+cilastatin, doripenem
Cephalosporins - 3rd gen ceftazidime, 4th gen cefepime
Aminoglycosides- amikacin, gentamicin, tobramycin
Quinolones- ciprofloxacin, levofloxacin, moxifloxacin
Monobactam- aztreonam

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2
Q

2nd Gen Cephalosporin with best anaerobic coverage (GIT)

A

Cefoxitin

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3
Q 
Partners:
Isoniazid - 
Methotrexate -
Alcohol - 
Cyclophosphamide -
A

Vit B6
Leukovorin
Thiamine
Mesna

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4
Q

Hypertension in pregnancy

A

Methyldopa
Hydralazine
Nifedipine
Labetalol

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5
Q

Beta 1 selective blockers

A 
BEAM
Bisoprolol, betaxolol
Esmolol
Atenolol
Metoprolol
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6
Q

Pheochromocytoma HPN control

A

Phenoxybenzamine, phentolamine, or labetalol

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7
Q

Meds which my cause drug-induced lupus

A 
HIPP
Hydralazine
Isoniazid
Procainamide
Penicillamine
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8
Q

Drugs causing gingival hyperplasia

A

Nifedipine
Cyclosporine
Phenytoin
Verapamil

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9
Q

Drugs with narrow therapeutic index

WALA CP PVT D

A 
Warfarin
Aminoglycosides
Lithium
Amphotericin B
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Theophylline
Digoxin
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10
Q

Class 1 Anti-arrhythmic drugs

Double quarter pounder with lettuce mayo tomato and more fries please

A

1a - disopyramide, quinidine, procainamide
1b - lidocaine, mexeletine, tocainide
1c - moricizine, flecainide, propefanone

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11
Q

Drugs causing agranulocytosis

A 
Clozapine
Co-trimoxazole
Colchicine
Aminopyrine
Phenylbutazone
PTU
Indomethacin
Tocainamide
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12
Q

Amiodarone toxicity

A 
Pulmonary fibrosis 
Paresthesias
Tremors
Thyroid dysfunction 
Corneal deposits 
Skin deposits
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13
Q

Loop diuretic toxicity

A 
OH DANG
Ototoxicity
Hypokalemia
Dehydration
Allergy to sulfa
Nephritis
Gout
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14
Q

Thiazide diuretics

A 
Hyper GLUC
Glycemia
Lipidemia
Uricemia
Calcemia
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15
Q

Potassium sparing diuretics

A 
SEAT
Spirinolactone
Eplerenone
Amiloride
Triamterene
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16
Q

Drugs that cause flushing

A

Vancomycin
Adenosine
Niacin
Calcium channel blockers

17
Q

Synergistic and bad anti hyperlipidemic

1- statin
2- resin
3- ezetimibe
4- niacin
5- fibrate
A 
Synergistic:
1+3
1+4
1+5
2+4
Bad
1+2
1+5
2+5
18
Q

Bactericidal antibiotics

A 
Very finely proficient at murder
Vancomycin 
Fluoroquinolones
Penicillins
Aminoglycosides
Metronidazole
19
Q

Bacteriostatic antibiotics

A 
Ecsttc
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracycline
Chloramphenicol
20
Q

Extended spectrum penicillin coverage

Amoxicillin/ampicillin

A 
HELPS kill Enteroccoci
Haemophilus influenzae
Escherichia coli
Listeria monocytogenes
Proteus mirabilis
Salmonella spp
Enterococci
21
Q

First gen cephalosporin coverage

A

Proteus mirabilis
Escherichia coli
Klebsiella pneumoniae

22
Q

1st gen cephalosporins

A 
Cefadroxil
Cefazolin
Cephalothin
Cephapirin
Cephadrine
Cephalexin
23
Q

2nd gen cephalosporin coverage

A 
HEN PEKS
H influenzae
Enterobacter aerogenes
Neisseria spp
Proteus mirabilis
E coli
Klebsiella pmeumoniae
Serratia marcescens
24
Q

2nd gen cephalosporins

A 
Cefamandole
Cefoxitin
Cefuroxime
Cefotetan
Cefaclor
Loracarbef
Cefprozil
Cefmetazole
Cefonicid
25
Q

3rd gen cephalosporins

A 
Cefetamet
Cefpodixin
Cefoperazone
Cefixime
Ceftriaxone
Ceftazidime
Cefotaxime
Ceftizoxime
Ceftibuten
26
Q

Anti pseudomonal cephalosporins

A

Ceftazidime
Cefepime
Cefoperazone

27
Q

Antibiotics of last resort

A 
Imipenem
Amikacin
Meropenem
Linezolid
Streptogramins
Vancomycin
28
Q

Protein synthesis inhibitors

Buy AT 30
CELLS at 50

A 
30s:
Aminoglycosides
Tetracyclines
50s:
Chloramphenicol
Erythromycin(macrolides)
Lincosamides (clindamycin)
Linezolid
Streptogramins
29
Q

DOC for Anaerobes

A

Clindamycin for above diaphragm

Metronidazole for below diaphragm

30
Q

Aminoglycosides

A 
GNATS can NOT kill anaerobes
Gentamicin
Neomycin
Amikacin
Tobramycin
Streptomycin

Nephrotoxic, Ototoxic, Teratogen

31
Q

Fluoroquinolones

Increasing generation = increasing gm (+) activity

A

1st gen: nalidixic acid - UTI
2nd gen: cipro, oflo, norfloxacin
Gm (-), gonococci, gm (+) cocci, mycoplasma
3rd gen: levofloxacin
less gm (-), more gm (+), strep, enterococci
4th gen: moxifloxacin
Broad spectrum, anaerobes

32
Q

Drugs causing pulmonary fibrosis

A 
BBBAN ME
Bleomycin
Busulfan
Bromocriptine
Amiodarone
Nitrofurantoin
Methotrexate
33
Q

Disulfiram reaction

A 
Clara took the Pre Medical Test this PM
Chlorpropamide
Cefo Perazone
         Mandole
          Tetan
Procarbazine
Metronidazole
34
Q

Cytochrome p450 inducers
Increased metabolism
Low half life

A 
PREG CS Baby
Phenytoin
Rifampicin
Ethanol
Griseofulvin
Carbamazepine
St John's Wort/ Smoking
Barbiturates
35
Q

Cytochrome p450 inhibitors
Decreased metabolism
High half life

A 
SICK GRAVE Q
Sulfonamides
Isoniazid
Cimetidine
Ketoconazole
Grapefruit juice (furanocoumarins)
Ritonavir
Amiodarone
Valproic acid
Erythromycin
Quinidine
37
Q

Drugs causing Gynecomastia

A 
Some dudes carry awesome knockers
Spironlactone
Digoxin
Cimetidine
Alcohol
Ketoconazole

BD MD (8 decks)

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