Pharma

Question 1

Anti pseudomonal

Answer 1

Penicillins- piptaz, ticarcillin
Carbapenem- meropenem, imipenem+cilastatin, doripenem
Cephalosporins - 3rd gen ceftazidime, 4th gen cefepime
Aminoglycosides- amikacin, gentamicin, tobramycin
Quinolones- ciprofloxacin, levofloxacin, moxifloxacin
Monobactam- aztreonam

Question 2

2nd Gen Cephalosporin with best anaerobic coverage (GIT)

Answer 2

Cefoxitin

Question 3

Partners:
Isoniazid - 
Methotrexate -
Alcohol - 
Cyclophosphamide -

Answer 3

Vit B6
Leukovorin
Thiamine
Mesna

Question 4

Hypertension in pregnancy

Answer 4

Methyldopa
Hydralazine
Nifedipine
Labetalol

Question 5

Beta 1 selective blockers

Answer 5

BEAM
Bisoprolol, betaxolol
Esmolol
Atenolol
Metoprolol

Question 6

Pheochromocytoma HPN control

Answer 6

Phenoxybenzamine, phentolamine, or labetalol

Question 7

Meds which my cause drug-induced lupus

Answer 7

HIPP
Hydralazine
Isoniazid
Procainamide
Penicillamine

Question 8

Drugs causing gingival hyperplasia

Answer 8

Nifedipine
Cyclosporine
Phenytoin
Verapamil

Question 9

Drugs with narrow therapeutic index

WALA CP PVT D

Answer 9

Warfarin
Aminoglycosides
Lithium
Amphotericin B
Carbamazepine
Phenobarbital
Phenytoin
Vancomycin
Theophylline
Digoxin

Question 10

Class 1 Anti-arrhythmic drugs

Double quarter pounder with lettuce mayo tomato and more fries please

Answer 10

1a - disopyramide, quinidine, procainamide
1b - lidocaine, mexeletine, tocainide
1c - moricizine, flecainide, propefanone

Question 11

Drugs causing agranulocytosis

Answer 11

Clozapine
Co-trimoxazole
Colchicine
Aminopyrine
Phenylbutazone
PTU
Indomethacin
Tocainamide

Question 12

Amiodarone toxicity

Answer 12

Pulmonary fibrosis 
Paresthesias
Tremors
Thyroid dysfunction 
Corneal deposits 
Skin deposits

Question 13

Loop diuretic toxicity

Answer 13

OH DANG
Ototoxicity
Hypokalemia
Dehydration
Allergy to sulfa
Nephritis
Gout

Question 14

Thiazide diuretics

Answer 14

Hyper GLUC
Glycemia
Lipidemia
Uricemia
Calcemia

Question 15

Potassium sparing diuretics

Answer 15

SEAT
Spirinolactone
Eplerenone
Amiloride
Triamterene

Question 16

Drugs that cause flushing

Answer 16

Vancomycin
Adenosine
Niacin
Calcium channel blockers

Question 17

Synergistic and bad anti hyperlipidemic

1- statin
2- resin
3- ezetimibe
4- niacin
5- fibrate

Answer 17

Synergistic:
1+3
1+4
1+5
2+4
Bad
1+2
1+5
2+5

Question 18

Bactericidal antibiotics

Answer 18

Very finely proficient at murder
Vancomycin 
Fluoroquinolones
Penicillins
Aminoglycosides
Metronidazole

Question 19

Bacteriostatic antibiotics

Answer 19

Ecsttc
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracycline
Chloramphenicol

Question 20

Extended spectrum penicillin coverage

Amoxicillin/ampicillin

Answer 20

HELPS kill Enteroccoci
Haemophilus influenzae
Escherichia coli
Listeria monocytogenes
Proteus mirabilis
Salmonella spp
Enterococci

Question 21

First gen cephalosporin coverage

Answer 21

Proteus mirabilis
Escherichia coli
Klebsiella pneumoniae

Question 22

1st gen cephalosporins

Answer 22

Cefadroxil
Cefazolin
Cephalothin
Cephapirin
Cephadrine
Cephalexin

Question 23

2nd gen cephalosporin coverage

Answer 23

HEN PEKS
H influenzae
Enterobacter aerogenes
Neisseria spp
Proteus mirabilis
E coli
Klebsiella pmeumoniae
Serratia marcescens

Question 24

2nd gen cephalosporins

Answer 24

Cefamandole
Cefoxitin
Cefuroxime
Cefotetan
Cefaclor
Loracarbef
Cefprozil
Cefmetazole
Cefonicid

Question 25

3rd gen cephalosporins

Answer 25

``` Cefetamet Cefpodixin Cefoperazone Cefixime Ceftriaxone Ceftazidime Cefotaxime Ceftizoxime Ceftibuten ```

Question 26

Anti pseudomonal cephalosporins

Answer 26

Ceftazidime Cefepime Cefoperazone

Question 27

Antibiotics of last resort

Answer 27

``` Imipenem Amikacin Meropenem Linezolid Streptogramins Vancomycin ```

Question 28

Protein synthesis inhibitors Buy AT 30 CELLS at 50

Answer 28

``` 30s: Aminoglycosides Tetracyclines 50s: Chloramphenicol Erythromycin(macrolides) Lincosamides (clindamycin) Linezolid Streptogramins ```

Question 29

DOC for Anaerobes

Answer 29

Clindamycin for above diaphragm Metronidazole for below diaphragm

Question 30

Aminoglycosides

Answer 30

``` GNATS can NOT kill anaerobes Gentamicin Neomycin Amikacin Tobramycin Streptomycin ``` Nephrotoxic, Ototoxic, Teratogen

Question 31

Fluoroquinolones Increasing generation = increasing gm (+) activity

Answer 31

1st gen: nalidixic acid - UTI 2nd gen: cipro, oflo, norfloxacin Gm (-), gonococci, gm (+) cocci, mycoplasma 3rd gen: levofloxacin less gm (-), more gm (+), strep, enterococci 4th gen: moxifloxacin Broad spectrum, anaerobes

Question 32

Drugs causing pulmonary fibrosis

Answer 32

``` BBBAN ME Bleomycin Busulfan Bromocriptine Amiodarone Nitrofurantoin Methotrexate ```

Question 33

Disulfiram reaction

Answer 33

``` Clara took the Pre Medical Test this PM Chlorpropamide Cefo Perazone Mandole Tetan Procarbazine Metronidazole ```

Question 34

Cytochrome p450 inducers Increased metabolism Low half life

Answer 34

``` PREG CS Baby Phenytoin Rifampicin Ethanol Griseofulvin Carbamazepine St John's Wort/ Smoking Barbiturates ```

Question 35

Cytochrome p450 inhibitors Decreased metabolism High half life

Answer 35

``` SICK GRAVE Q Sulfonamides Isoniazid Cimetidine Ketoconazole Grapefruit juice (furanocoumarins) Ritonavir Amiodarone Valproic acid Erythromycin Quinidine ```

Question 37

Drugs causing Gynecomastia

Answer 37

``` Some dudes carry awesome knockers Spironlactone Digoxin Cimetidine Alcohol Ketoconazole ```