Pharm Week 1 Flashcards
What are the properties of an ideal drug? (3)
1) Effectiveness- is the drug effective?
2) Safety- Side effects?
3) Selectivity- drug elicits only the response for which it is given
What is the therapeutic objective of a drug?
to provide maximum benefit with minimum harm
Factors that determine the intensity of drug responses ?
1) Administration
2) Pharmacokinetics- impact of the body on drugs
3) Pharmacodynamics- impact of drugs on the body
4) Sources of individual variation
What are the four major pharmacokinetic processes?
1) Drug absorption
2) Drug distribution
3) Drug metabolism
4) Drug excretion
3 CNO expectations in medication administration
1) Authority- does the medication require an order? is it a controlled act?
2) Safety- have I considered the risk and adverse reactions? Have I provided the patient with education? Are there strategies to minimize the risk of harm?
3) Competence- do I have the knowledge, skill and judgment?
What is a PRN decision?
as needed
What is pharmacokinetics?
The effect of the body on a drug
What is pharmacodynamics?
The effect of drugs on the body
What do you find out in a pre-administration assessment?
1) baseline data to evaluate therapeutic effects
2) collection of baseline data to evaluate adverse effects
3) identification of high-risk patients
4) assessment of the patient’s ability for self-care
When new drugs are developed who do we have limited information on?
Women and children
What is absorption ?
Movement of a drug from its site of administration into the blood
What is P-glycoprotein?
transmembrane protein that transports a wide variety of drugs out of cells
