pharm: specific toxicity treatments Flashcards

1
Q

acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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2
Q

AchE inhibitors, organophosphates

A

atropine > pralidoxime

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3
Q

amphetamines (basic)

A

NH4Cl (acidify urine)

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4
Q

anitmuscarinic, anticholinergic agents

A

physostigmine, control hyperthermia

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5
Q

arsenic

A

dimercaprol, succimer

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6
Q

benzodiazepines

A

flumazenil

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7
Q

beta blockers

A

saline, atropine, glucagon

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8
Q

carbon monoxide

A

100% O2, hyperbaric oxygen

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9
Q

copper

A

penicillamine, trientine

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10
Q

cyanide

A

nitrite + thiosulfate, hydroxocobalamin

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11
Q

digitalis (digoxin)

A

anti-dig Fab fragments

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12
Q

gold

A

penicillamine, dimercaprol (BAL), succimer

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13
Q

heparin

A

protamine sulfate

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14
Q

iron

A

deferoxamine, deferasirox, deferiprone

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15
Q

lead

A

EDTA, dimercaprol, succorer, penicillamine

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16
Q

mercury

A

dimercaprol, succimer

17
Q

methanol, ethylene glycol (antifreeze)

A

fomepizole > ethanol, dialysis

18
Q

methemoglobin

A

methylene blue, vitamin C

19
Q

opioids

A

naloxone

20
Q

salicylates

A

NaHCO3 (alkalinize urine), dialysis

21
Q

TCAs

A

NaHCO3

22
Q

warfarin

A

vitamin K (delayed effect), fresh frozen plasma (immediate)