pharm: specific toxicity treatments Flashcards by Beth Patterson

Q

acetaminophen

A

N-acetylcysteine (replenishes glutathione)

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Q

AchE inhibitors, organophosphates

A

atropine > pralidoxime

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Q

amphetamines (basic)

A

NH4Cl (acidify urine)

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Q

anitmuscarinic, anticholinergic agents

A

physostigmine, control hyperthermia

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Q

arsenic

A

dimercaprol, succimer

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Q

benzodiazepines

A

flumazenil

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Q

beta blockers

A

saline, atropine, glucagon

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Q

carbon monoxide

A

100% O2, hyperbaric oxygen

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Q

copper

A

penicillamine, trientine

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Q

cyanide

A

nitrite + thiosulfate, hydroxocobalamin

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Q

digitalis (digoxin)

A

anti-dig Fab fragments

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Q

gold

A

penicillamine, dimercaprol (BAL), succimer

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Q

heparin

A

protamine sulfate

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Q

iron

A

deferoxamine, deferasirox, deferiprone

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Q

lead

A

EDTA, dimercaprol, succorer, penicillamine

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Q

mercury

A

dimercaprol, succimer

Q

methanol, ethylene glycol (antifreeze)

A

fomepizole > ethanol, dialysis

Q

methemoglobin

A

methylene blue, vitamin C

Q

opioids

A

naloxone

Q

salicylates

A

NaHCO3 (alkalinize urine), dialysis

Q

TCAs

A

NaHCO3

Q

warfarin

A

vitamin K (delayed effect), fresh frozen plasma (immediate)