Pharm Review

Question 1

What are the adverse effects of thiazide diuretics?

Answer 1

Hyperglycemia (careful w/ diabetics)
Inc. LDL (careful if dyslipidemia)
Inc. uric acid
Hypokalemia
* Do not combine w/ lithium as inc. risk of lithium toxicity

Question 2

What is the contraindication for thiazide and loop diuretics?

Answer 2

Sulfa allergy

Question 3

How do thiazide diuretics help with osteoporosis?

Answer 3

Dec. calcium excretion by kidneys and stimulate osteoblasts

Question 4

What is the rare SE with captopril?

Answer 4

Agranulocytosis, neutropenia and leukopenia

Question 5

What is the first line medication for Raynaud’s phenomenon?

Answer 5

CCBs

Question 6

How is pedal edema associated with Amlodipine and Nifedipine treated?

Answer 6

Reduce dose
Take later in the day
Improved with lying down

Question 7

Alpha-blockers end in which suffix?

Answer 7

-osin
(Doxazosin, tamsulosin, prazosin, terazosin)

Question 8

Rhinitis medicamentosa occurs after how many days/weeks use of decongestants?

Answer 8

Greater than 3 days
(Contraindicated w/ htn, CAD (angina, MI))

Question 9

Aspirin is contraindicated under what yr for the risk of Reye syndrome?

Answer 9

12 y.o.