Pharm: Oncology Flashcards
1
Q
what are tumor markers good for?
A
surveillance, therapy monitoring, directing therapy, prognosis
2
Q
which tumor markers are hormone?
A
Beta-HCG
3
Q
which tumor markers are oncogenes?
A
BRCA 1 & 2
4
Q
alpha fetoprotein (AFP)
A
antigen
normally in fetal GI tract (which other tumor mark is too?)
also found in pts w/ hepatocellular carcinoma
5
Q
beta-HCG
A
hormone
- normally found in pregnancy + test
- germ cell tumors in males
6
Q
Bence Jones protein
A
antigen
- found in urine
- used to detect and monitor multiple myeloma
7
Q
BRCA 1&2
A
oncogene
-either = increased risk for breast or ovarian cancer
8
Q
cancer antigen 19-9
A
antigen
-diagnosis, monitoring, and evaluation of tx of pancreatic and hepatobiliary CA
9
Q
cancer antigen 125
A
antigen
- elevated in ovarian CA
- used for dx, monitor and surveilance
10
Q
carcinoembryonic antigen
A
antigen
- produced in fetal GI tract (along w/ which other tumor marker?)
- colorectal cancer
- elevated baseline in smokers
11
Q
prostate specific antigen
A
antigen
- prostate CA
- PSA levels correspond closely w/ tumor bulk
