Pharm II lecture 4

Question 1

tenesmus

Answer 1

The feeling of having to have a bm but is empty

Question 2

rectum is usually involved

Answer 2

UC

Question 3

transmural disease

Answer 3

crohn’s disease

Question 4

skip lesion

Answer 4

Crohn’s disease

Question 5

Severity for UC

Answer 5

-number of stools per day
-presence of blood
-systemic disturbance

Question 6

crohn’s disease severity

Answer 6

-ability to complete normal activity
-ability to tolerate oral nutrition
-weight loss

Question 7

trigger for flares

Answer 7

smoking and NSAIDs

Question 8

corticosteroid

Answer 8

mild treatment for UC

Question 9

corticosteriod meds

Answer 9

budesonide foam, hydrocortisone foam/enema

Question 10

AE of corticosteroid

Answer 10

leukocytosis and hyper glycemia

Question 11

limit the use of corticosteroids for

Answer 11

4 months

Question 12

instruction for intake of corticosteroid

Answer 12

swallow whole, do not crush or chew

Question 13

budesonide (entocort)

Answer 13

oral - designed to release in terminal ileum or colon

Question 14

Aminosalicylate

Answer 14

primarily used for UC

Question 15

prototypical aminosalicylate

Answer 15

sulfasalazine

Question 16

Which meds cause yellow/orange discoloration of urine

Answer 16

sulfasalazine

Question 17

foam

Answer 17

rectum to the sigmoid

Question 18

enema

Answer 18

up to the splenic flexure

Question 19

canasa suppository

Answer 19

retain at least 1-3 hours

Question 20

rowasa enema

Answer 20

retain for 8 hours

Question 21

methotrexate

Answer 21

used for chron’s disease

Question 22

contraindication for methotrexate

Answer 22

pregnancy

Question 23

box warning for methotrexate

Answer 23

hepatoxicity w/alcohol, GI toxicity

Question 24

Thiopurines

Answer 24

used for UC and crohn’s

Question 25

What needs to be monitored when you use Thiopurines

Answer 25

TPMT - metabolize azothioprine

Question 26

box warning for biologics

Answer 26

TB, hepatitis, lymphoma

Question 27

MOA of xelijanz

Answer 27

JAK inhibitor

Question 28

cyclosporine usage

Answer 28

attempt to avoid volectomy in pt with UC failing corticosteroid therapy

Question 29

mild UC treatment

Answer 29

5- ASA

Question 30

Mild treatment for Crohn's

Answer 30

Budesonide (entocort)

Question 31

MTX is used for

Answer 31

moderate/severe Crohn's disease

Question 32

Diverticula

Answer 32

sac like profusion of the colonic wall

Question 33

diverticulosis

Answer 33

presence of diverticula

Question 34

diverticulitis

Answer 34

inflammation or infection of diverticula