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STEP 1 > Pharm GI > Flashcards

Pharm GI Flashcards

1
Q

Loperamide (MOA)

A

Imodium
Binds to mu opiate R in colonic myenteric plexus, slowing peristalsis. (Antidiarrheal)
This inhibits Ach release from myenteric plexus neurons.
Unlike others opiates Loperamide does NOT cross the BBB.

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2
Q

Bismuth Subsalicylate (MOA)

A

Stimulates intestinal fluid absorption and inhibits prostaglandin synthesis. (antispasmodic effect)

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3
Q

Octreotide (MOA)

A

Somatostatin analog
Reduces secretion of pancreatic and GI hormones

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4
Q

Cholestyramide

A

Bile acid sequestrants
Binds bile acid in intestines (used for bile-acid diarrhea)

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STEP 1 (18 decks)

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