Pharm: Cardio Flashcards

1
Q

Alpha Blocks MOA

A

antagonizes peripheral alpha-1 adrenergic receptors

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2
Q

What are the first line meds uses for AA w/HTN?

A
  • Diuretics (Thiazide - HCTZ)
  • Calcium Channel Blocker
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3
Q

Alpha Blockers: Cautions

A
  • NO pregnancy & hypotension if used w/ Sildenofil (Viagra)
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4
Q

List Alpha Blocker Meds

A
  • Prazosin
  • Terazosin
  • Doxazosin
  • Tamsulosin
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5
Q

Alpha Blockers work mostly in:

A
  • vascular SM
  • bladder neck
  • prostate gland
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6
Q

If a patients has a sulfa allergy, what should you avoid & what should you use?

A
  • avoid HCTZ
  • uses CCB
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7
Q

Prazosin: Uses

A

-HTN
- BPH
- Nightmares, PTSD

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8
Q

Terazosin: Uses

A
  • HTN
  • BHP
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9
Q

Doxazosin: Uses

A
  • HTN
  • BPH
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10
Q

Tamsulosin: Uses

A
  • BPH
  • nephrolithiasis
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11
Q

When do you take Prazosin?

A

1st dose at bedtime

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12
Q

When do you take Terazosin?

A

@ bedtime

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13
Q

When do you take Doxazosin?

A

@ bedtime

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14
Q

When do you take Tamsulosin?

A

30 mins after eating in the morning

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15
Q

Tamsulosin: Common Rxns

A
  • abnormal ejaculation
  • dizziness
  • Rhinitis
  • Cough
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16
Q

Beta Blockers are located where & causes what?

A
  • cardiac nodal tissue (Incr CO)
  • conducting system (decr HR)
  • contracting myocytes (reduce contractility)
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17
Q

BB: Relative Contraindications

A
  • Asthma & COPD (especially non-selective Beta Blockers–>Carbetalol)
  • Cocaine Use
  • Diabetes Mellitus
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18
Q

BB: Absolute Contraindications

A

Bradycardia or heart block

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19
Q

List the 1st gen non-selective BB

A
  • Propranolol
  • Timolol
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20
Q

List the 2nd gen selective B1B

A
  • Atenolol
  • Metoprolol
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21
Q

List the 3rd gen non-selective B & A1 Blocker)

A

Non-selective
- carvedilol
- Labetalol

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22
Q

List BB meds

A
  • Atenolol
  • Metoprolol
  • Propranolol
  • Carvedilol
  • Labetalol
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23
Q

BB: Cautions

A
  • avoid abrupt discontinuation can cause rebound tachycardia
  • DON’T USE in 2nd/3rd degree AV block, decomp HF, sinus brady
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24
Q

List the selective antagonist for B1 adrenergic receptor meds

A
  • Atenolol
  • Metoprolol
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25
Q

Atenolol: Uses

A
  • HTN
  • Angina
  • CV event, prevention, post MI (2ndary)
  • migraine HA, prophy
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26
Q

Metoprolol: Uses

A
  • HTN
  • Angina
  • CHF
  • *migraine HA prophy

Consider giving a BB if a NEW diastolic murmur to decr pulsatile flow in case of a potential aortic dissection “tearing chest (or back) pain”

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27
Q

List the non-selective antagonist for B1& B2 adrenergic receptor meds

A
  • Propranolol
  • Carvedilol
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28
Q

Propranolol: Uses

A
  • HTN
  • Angina
  • CV prevention, post-MI
  • AFib/flutter
  • supraventricular arrhythmias
  • migraine HA prophy
  • essential tremor
  • idiopathic hypertrophic subaortic stenosis (IHSS)
  • pheochromocytoma, adjunct tx
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29
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50
Q

Initial Tx: black pts

A

CCB or thiazide diuretic

50
Q

Initial Tx: nonblack pts < 60yo
(**)

A

ARB or ACE inhibitor

51
Q

Initial Tx: Pts w/ chronic kidney dz
(**)

A

ARB or ACE inhibitor

51
Q

Initial Tx: Pts w/ CAD

A

BB and ARB or ACE inhibitor

51
Q

Initial Tx: w/ HF

A

ARB or ACE inhibitor & BB & spironolactone

51
Q

Initial Tx: Nonblack Pts >/= 60yo

A

CCB, thiazide diuretic, ARB or ACE inhibitor

52
Q

Initial Tx: Pts w/ DM

A

ARB or ACE inhibitor
(CCB or thiazide diuretic in black pts)

53
Q

Initial Tx: w/ history of stroke

A

ARB or ACE inhibitor