pharm antibiotics Flashcards

1
Q

what are the 3rd gen cephlasporin?

A

triax, tax, taz

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2
Q

which of 3rd gen ceph are oral?

A

cefdinir and cefpoxime

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3
Q

what 2nd gen ceph is PO

A

cefuroximine azetil

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4
Q

what 1st gen ceph is po /oral and what 1st gen is IV

A

cephalaxine oral, cefazolin IV

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5
Q

are cephlasporins Beta lactams? similar adverse effects?

A

yes. yes.

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6
Q

Cephlasporins work how?

A

bind to PBP, CELL WALL falls

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7
Q

what allergy is the most common type of allergy among antibiotics/antimicrobials

A

penicillin

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8
Q

can a patient with a PCN allergy get another Beta lactam, names?

A

yes. ceph, carb, monopen

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9
Q

True PCN allergy, give Nafcillin or Oxacillin (anti-staph PCN) or a cephlasporin?

A

no. a cephlasporin (good chance it would be ok)

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10
Q

penicillin ases address how?

A

add beta lactam inhibitors

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11
Q

cephlasporins are __ against beta lactams?

A

stable.

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12
Q

are cephlasporins safe for kids?

A

yes except one.

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13
Q

Pip/tazo, does this get into the CSF? If infected with Pseudomonas, would you want this antimicrobial?

A

no. no.

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14
Q

If CNS/CSF/Pseudomonas infection, tx with Tazo/Pip or later gen Cephlasporins??

A

tazo/pip=x csf, later gen ceph goes to CSF! Maybe carbapenam.

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15
Q

which ceph =x req renal dosing?

A

ceftriaxone.

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16
Q

Cephlasporins have NO activity against ?

A

LAME OR MALE,

LISTERIA, ATYPICALS,

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17
Q

Listeria drug of choice

A

amoxicillin and ampicillin

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18
Q

Do betalactams cover atypicals??

A

Nope. they are CLam.

Chlamydia, Listeria, Mycoplasma

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19
Q

Cephlasporins have NO activity against ?

A

LAME OR MALE,

LISTERIA, ATYPICALS, mrsa (except ceftaroline), Enterococcus

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20
Q

amoxicillin and ampicillin

A

Listeria, enterococus

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21
Q

what one beta lactam covers MRSA?

A

Ceftaroline

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22
Q

w/PCN allergy and LAME bug, can cephlasporins be used?

A

NOPE, no coverage for LAME, lysteria/atypicals (chlyamidyia, mycoplasma)

23
Q

what is 1st gen ceph use for?

A

MSSA! G+ !!

24
Q

what is 3rd gen ceph used for

A

(G+) Strep Pneumo!!! (some G - )ECOLI!

25
when use 6th gen ceph?
when can't use carbapenems (CRE) ?
26
1st gen ceph and anti staph are both D.O.C for ?
staphlococcus : MSSA
27
what is the drug of choice for staph: MSSA?
1st gen ceph (cef and anti staph PCN (amox, Amp)
28
group A strep (strep throat) start with a ___, but if allergy, what can be used?
PCN (amoxicillin), allergy then can do a 1st gen ceph ( cephalexin, or cefazolin)
29
which gen ceph for strep pnemonia
3rd
30
what is PEK
proteus
31
Antistaph and 1st gen ceph are drug of choice for what? which is preferred?
MSSA, 1st gen ceph preferred (last longer, less side effects)
32
mssa infection what IV agent recommend for pt with mild non anaphalactic PCN allergy
cefazolin
33
2nd gen ceph, which is oral and is it not
cefuroximide oral
34
3rd gen cephlasporin oral agent
cefdinir, also cefpodomire
35
3rd gen. ceph coverage and what is designed for
resist b lactam ace ,
36
what 3rd gen ceph dose 1x day
ceftriax
37
what 3rd gen issue w kids and which?
ceftriaxone, kernicteris
38
what 3rd gen issue w kids and which?
ceftriaxone bound to albumin in kidneys, kernicteris
39
which ceph =x req renal dosing? how many dose per day?
ceftriaxone, one (unique)
40
what does ceph triaxe cover and not cover
pek+h+m+space (no pseudo), tc Ghonorea
41
ceftriaxone can be use for s pnemoniae?
yes
42
What is metronidazole used for?
anearobes G+ and G-
43
what cephazolins add metro to for anaerobic coverage?
cephapine, cefazolin, ceftriaxone
44
does pip/tazo need additional coverage with metronidazole?
no
45
what cephasolins could benefit from metronidazole? also
1st or second generation cephlasporin
46
add metro to these to treat anearobes in gut
floroquinilones: ciprofloxin, levoflox
47
metronidazole + tinidazole together treats what?
protozoa and parasites: trichomonas, gardinerella, entamoeba
48
drug interaction with Metronidazole with ___ product then ___ what happens?
alcohol (dinatab or robotussin or alcohol) to disulferam -->N/V/flushing and cardiac.no aclcohol on the metro
49
metronidazole drug of choice
trichomonas vaginialis, also for aneorobes.
50
clindamycin can be taken how?
every way. bac stat
51
aneorobic bacterias
bateroides, fusobacterium, provetella, clostridium, actinomyces, lactobacillis, proprionibacterium, pepto & peptostrepto
52
metro or clinda for csf?
metro. clinda =x brain
53
what can metro not treat?
no staph no strep. metro aneorobes.