Pharm Flashcards

1
Q

Lipitor / atorvastatin

A

Hmg/coa reductase inhibitor. Blocks production of cholesterol

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2
Q

What supplement should be taken with atorvastatin which causes coenzyme depletion up to 50% within 30 days

A

100mg CoQ10. 10 to 30mg can prevent initial decline.

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3
Q

What medication interferes with atorvastatin absorption

A

Magnesium and aluminum containing antacids. Take lipitor 2 hours before or after any antacids.

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4
Q

Niacin is ..

A

Vitamin b3. Used to lower cholesterol.

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5
Q

Niacin taken along with ___ can cause myopathy (muscle disorders) amd can enhance cholesterol lowering effects.

A

Hmg-coa reductase inhibitors.

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6
Q

Vitamin a blood levels increased over time when used with ___. People who take ___ should get blood work monitored if they intend to supplement with vitamin a.

A

Hmg-coa reductase inhibitors

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7
Q

Prilosec / omeprqzole

A

Proton pump inhibitor. Blocks production of stomach acid.

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8
Q

Folic acid is needed by the body to utilize ___

A

Vitmin b12

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9
Q

what medication inhibits absorption of folic acid?

A

Antacids

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10
Q

People taking antacids are advised to supplement with ___

A

Folic acid

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11
Q

Omeprazole interferes with the absorption of ___ from food (not suppliments)

A

Vitamin b12

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12
Q

The fall of vitamin b12 status may result from ___

A

The decrease in stomach acid required for vitamin b12 absorption from food caused by the drug (antacids, omeprazole etc)

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13
Q

People taking omeprazole and related antacids should ___

A

either take a vitamin b12 supplement or get levels checked yearly

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14
Q

10 to 50mg per day of vitamin b12 can __

A

Protect against drug induced vitamin depletion

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15
Q

What suppliment decreases omperazole blood levels by accelerating the drugs metabolism?

A

St. Johns wort

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16
Q

People taking omperazole may increase absorption of ____ by drinking ____ or other acidic liquids with _____ containing foods.

A

Vitamin b12, cranberry juice, vitamin b12

17
Q

Montelukast

A

LTRA - leukotriene receptor antagonist used to treat asthma and allergies

18
Q

Lansoprazole

A

Proton pump inhibitor

19
Q

Omeprazole and lansoprazole taken for several days led to a near - total loss of ___ in healthy people and interfered with the ___ of a single administration of 120mg of beta-carotene.

A

Stomach acid, absorption

20
Q

What blood levels should be checked for people taking acid-blocking drugs for long periods of time

A

Carotenoid blood levels

21
Q

What recommendation should you give for people taking acid blocking medications

A

Eat plenty of fruits and vegetables and consider supplementing with carotenoids

22
Q

Folic acid is needed by the body to ____

A

Utilize vitamin b12

23
Q

What to antacids inhibit?

A

Folic acid absorption

24
Q

People taking antacids should suppliment with ___

A

Folic acid

25
Q

Lansoprazole dosing

A

30 minutes before a meal dame time every day.

26
Q

Venlafaxine

A

Depression

27
Q

L-tryptophan

A

Essential amino acid, serotonin precursor, biosynthesis of protein. Must be obtained from diet.

28
Q

5-HTP (hydroxytryptophan)

A

Serotonin reuptake inhibitor, amino acid. Converts protein to serotonin in the brain.

29
Q

Venlafaxine with what SRI / herbs should be avoided.

A

5-hydroxytryptophan, L-Tryptophan, St. Johns wort, sour date nut.

30
Q

Why is 5-HTP better than L-Tryptophan

A

Crosses blood brain barrier at higher rate, converts serotonin more efficiently with stronger effects.

31
Q

What is serotonin syndrome

A

Over production of serotonin because of a medication or combo of meds. Extreme nerve cell activity.

32
Q

When to take Valsartan

A

Ingestion of food woth valsartan may decrease the maximum blood level of the drug by %50 therefore should be taken an hour before or two hours after a meal.

33
Q

Crestor - rosuvastatin

A

Reduce cholesterol and fat levels in the blood and to increase HDL (good cholesterol) levels. Class - HMG-CoA reductase inhibitor.

34
Q

Niacin and crestor

A

High doses of niacin (higher than normal nutritional suppliment doses) isn’t recommended to take with crestor because of increased risk of rhabdomyolysis and kidney damage. Greater risk in elderly or if preexisting kidney damage.

35
Q

Simvastatin

A

HMG-CoA reductase inhibitor blocks bodys production of cholesterol. Lower elevated cholesterol reduces risk of heart attack / death