Pharm Flashcards
What is the difference between topical and transdermal drug therapy?
Topical = dermal issue Transdermal = systemic issue
What is the correct order of most to least moisturizing vehicles?
Occlusive dressing Ointment Cream Lotion Gel Spray Solution
When should a wet dressing be used?
With an oozing/weeping wound to promote evaporation
Which acne medications reduce the number of bacteria on the skin?
Benzoyl peroxide
Topical abx
Oral abx
Which acne medications reduce sebum production or presence?
Benzoyl peroxide
Isotretinoin
Which acne medications increase cell turnover?
Benzoyl peroxide
Tretinoin
Adalapene
Salicylic acid
What is a low concentration of salicylic acid used for?
Abnormal keratinization i.e. corns
What is a medium concentration of salicylic acid used for?
Skin peeling
What is a high concentration of salicylic acid used for?
Caustic effects i.e. plantar warts
What is the MOA of finasteride?
Inhibits conversion of testosterone to dihydrotestosterone (DHT)
What is the MOA of minoxidil?
Stimulates follicles, follicular cycling, and VEGF
What is the MOA of eflronithine?
Inhibits enzyme responsible for hair cell division
What size tube should be prescribed BID x1 week for lesions of the head and neck or one arm or hands and feet?
15gm
What size tube should be prescribed TID x2 weeks for lesions of the head and neck or one arm or hands and feet?
30gm
What size tube should be prescribed BID x4 weeks for lesions of the head and neck or one arm or hands and feet?
45gm
What size tube should be prescribed BID x1 week for lesions of the trunk?
80gm
What size tube should be prescribed TID x2 weeks for lesions of the trunk?
160gm
What size tube should be prescribed BID x4 weeks for lesions of the trunk?
240gm
What size tube should be prescribed BID x1 week for lesions of one leg?
30gm
What size tube should be prescribed TID x2 weeks for lesions of one leg?
90gm
What size tube should be prescribed BID x4 weeks for lesions of one leg?
120gm
What size tube should be prescribed BID x1 week for lesions of the body?
180gm
What size tube should be prescribed TID x2 weeks for lesions of the body?
454gm
What size tube should be prescribed BID x4 weeks for lesions of the body?
454gm
What factors are decreased in elderly skin?
Blood flow
Sebaceous glands
Sweat glands
What do these decreased factors lead to?
Thin and damaged skin w/increased risk for systemic absorption of topical agents leading to toxicity
What are the ASEs of topical corticosteroids?
Skin atrophy
Telangiectasia
Striae
When are topical corticosteroids CI?
Skin breaks/infections
What drugs are considered miscellaneous topical antipruritics?
Pramoxine
Diphenhydramine
Doxepin
What are the ASEs of pramoxine?
Burning
Rash
What formulation of diphenhydramine should be used?
PO