Pharm

Question 1

Bendroflumethiazide

Uses and side effects

Answer 1

Thiazide diuretic - (also causes vasodilation)

Uses:

1) Hypertension (2.5mg OD)
2) Mild heart failure (5-10mg OD)

S.E
postural hypotension
hyponatraemia, hypokalaemia, hypercalcaemia
gout
impaired glucose tolerance
impotence
fatigue
pulmonary oedema
pneumonitis

Question 2

Amikacin - Type, S.E. Uses

Answer 2

Aminoglycoside antibiotic

Joint infections, intraabdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis

Can cause hearing loss, balance problems, and kidney problems

Question 3

Name 3 features of severe alcohol withdrawal

Answer 3

Hallucinations
Withdrawal seizures - (generalised tonic-­‐clonic)
Delirium tremens
§ Anxiety
§ Tremor
§ Sweating
§ Vivid and terrifying visual and sensory HALLUCINATIONS
(usually of animals and insects)

Question 4

What is the treatment of severe alcohol withdrawal ? (3)

Answer 4

Chlordiazepoxide (benzo)

Barbiturates if Benzo not effective

Thiamine (Pabrinex)

Question 5

Outline the symptoms of salicylate poisoning

Answer 5

Early Symptoms
o Flushed
o Fever
o Sweating
o Hyperventilation
o Dizziness
o Tinnitus
o Deafness

• Later Symptoms
o Lethargy
o Confusion
o Convulsions
o Drowsiness
o Respiratory depression
o Coma

Question 6

What would you find on physical examination of a patient with salicyate poisoning?

Answer 6

On physical examination 
#• Fever
• Tachycardia
• Hyperventilation
• Epigastric tenderness

Question 7

Name one long actin insulin analogue

Answer 7

Glargine (Lantus)

Question 8

What drug might cause blurred vision

Answer 8

anti-muscarinic agents (e.g. atropine)

Question 9

What drug might cause cough ?

Answer 9

ACE inhibitors

Question 10

What drug might cause tremor?

Answer 10

alpha-adrenergic receptor agonists (e.g. salbutamol

Question 11

What drug might cause rash

Answer 11

ampicillin and amoxicillin in glandular fever.

Question 12

How would you treat CAP?

Answer 12

co-amoxiclav and clarithromycin

Question 13

Which 2 AB’s must be sustained for 6months in TB?

Answer 13

Rifampicin and Isoniazid.

Question 14

Name 3 common nephrotoxic drugs that should be stopped in AKI

Answer 14

ACE inhibitors,
NSAIDs,
gentamicin