Pharm 607 Smoking Cessation

Question 1

how many cigarettes would justify 21mg nicotine patches

Answer 1

> 10

Question 2

What dosage would Varenicline be prescribed at for basal/controller?

Answer 2

0.5mg (up to 1mg BID in 1st week) for a min of 12 weeks

Question 3

What dosage would Wellbutin be prescribed at for basal/controller?

Answer 3

150mg extended release for min 12 weeks

Question 4

Chantix and Wellbutrin have what side effects/risks?

Answer 4

Chantix: Vivid dreams, hypersensitivity to class/agitation
can lower seizure threshold.

Wellbutrin: sleep issues, can lower seizure disorder

Question 5

Wellbutrin can assist with what (other than smoking cessation)

Answer 5

beneficial w/ coexisting depression disorder and help with weight loss

Question 6

What class would nicotine patches fall under?
Varenicline/Chantix?
Wellbutrin/Bupropion?

Answer 6

patches. Full agonist of alpha-4-beta nicotinic acetylcholine receptor

Chantix: partial agonist of alpha-4-beta nicotinic acetylcholine receptor

Bupropion (neuronal uptake inhibitor of norepinephrine and dopamine)