Analgesics and NSAIDS

Question 1

What are the side effects of Morphine Sulate?

Answer 1

Decreased BP
Respiratory depression
Urinary retention
Constipation
Orthostatic Hypotension
Constipation

Question 2

What can be used to reverse effects of opioids?

Answer 2

Naloxone (Narcan)

Question 3

How do opioids work?

Answer 3

bind with receptors in the brain and spinal cord that are associated with pain. Moderate opioid analgesics are similar to morphine, however pain control is less effective and the potential for respiratory depression is less

Question 4

What are these opioid analgesics combined with?
Percodan
Percocet
Combunox

Lortab
Vicodin
Vicoprofen

Answer 4

Percodan: Oxycodone w/ aspirin
Percocet: Oxycodone w/ acetaminophen
Combunox: Oxycodone w/ ibuprofen

Lortab: Hydrocodone w/ acetaminophen
Vicodin: Hydrocodone w/ acetaminophen
Vicoprofin: Hydrocodone w/ Ibuprofen

Question 5

How does Narcan work?
how long is the response?
when is the peak?

Answer 5

Opioid antagonist blocks opiate receptor sites.
1-2 min
Peak 20-60 min

Question 6

How does aspirin work?

Answer 6

nonselective cyclooxyrgenase inhibitor that decrease the formation of prostaglandins involved in the production of inflammation, pain and fever. Inhibits platelet aggregation

Question 7

What is aspirin contraindicated with?

Answer 7

hypersensitivity
pregnancy
hx of GI ulcer, PUD (or any bleeding disorder)
*children with a recent hx of viral infection (i.e. influenza, chicken pos etc), has been associated with Reyes Syndrome