Pharm

Question 1

acetaminophen

Answer 1

tx: N-acetylcysteine (replenishes glutathione)

Question 2

AChE inhibitors, organophosphates (OPP)

Answer 2

tx: atropine>pralidoxime

Question 3

amphetamines (basic)

Answer 3

NH4Cl (acidify urine)

Question 4

antimuscarinic, anticholinergic agents

Answer 4

physostigmine salicylate, control hyperthermia

Question 5

Benzodiazepines

Answer 5

Flumazenil

Question 6

Beta-blockers

Answer 6

glucagon

Question 7

Carbon monoxide (CO)

Answer 7

100% O2, hyperbaric O2

Question 8

copper, arsenic, gold

Answer 8

(D-) Penicillamine

Question 9

cyanide (burnt almond)

Answer 9

Nitrite + thiosulfate, hydroxycobalamin

Question 10

digitalis (digoxin)

Answer 10

Anti-dig Fab fragments

Question 11

Heparin

Answer 11

protamine sulfate

Question 12

Iron

Answer 12

Deferoxamine, Deferasirox

Question 13

Lead

Answer 13

EDTA (edetate calcium disodium), dimercaprol, succimer, penicillamine

Question 14

Mercury, arsenic, gold

Answer 14

Dimercaprol BAL, succimer

Question 15

methanol, ethylene glycol (antifreeze)

Answer 15

Fomepizole>ethanol, dialysis

Question 16

methemoglobin

Answer 16

methylene blue, Vit C

Question 17

opioids

Answer 17

Naloxone, Naltrexone

Question 18

salicylates

Answer 18

NaHCO3 (alkalinize urine), dialysis

Question 19

TCAs

Answer 19

NaHCO3 (plasma alkalinization)

Question 20

tPA, streptokinase, urokinase

Answer 20

aminocaproic acid (ACA)

Question 21

Warfarin

Answer 21

Vit K (delayed effect), fresh frozen plasma-FFP (immediate)

Question 22

atropine

Answer 22

(tertiary amine) physostigmine–can reverse CNS and peripheral symptoms of severe atropine toxicity

Question 23

heroin OD

Answer 23

contricted pupils, stupor, unresponsive