PHARM Flashcards
Metronidazole kills
Anerobes and protozoa
Gut bugs (c.Dif, H.Pylori, Enterobacter)
Protozoa (Trichomonas Vaginalis, Entamoeba, Giardia…)
No Alcohol with either drug. Nausea, Vomiting, Flushing, Tachycardia + SOB
Corticosteroid risks to the eye
Cataracts and Glaucoma
Cataracts: Glucocorticoids initiate gene transcription anomalies in corneal epithelial cells that leads to over production, migration of cells and possibly to changes in protein production. Exact mechanism isn’t yet eludicated but corticos do cause epithelial cataracts and they’re usually situated on the central posterior lens.
Glaucoma: Trabecular cells swell under the influence of corticos, as do many other tissues.
Its a particular problem with trabecular cells in that their swelling closes off the canals of schlemm reducing drainage from the posterior eye to the anterior and increasing pressure in the back, squishing the retina and killing it off.
Anyone with other comorbid glaucoma risk (DM, Age, Open Angle Glaucoma) should not receive cortio rx lightly.
Effect of discontinuing Clonadine abruptly?
Rebound HTN
Its a central Alpha Agonist
PENTAZOCINE
Partial Opiate Agonist Pain Reliever
Synthetic Narcotic of the Benzomorpan class. These all end in “CINE”
prone to eliciting psychosis and delirium and
Respiratory Depression like a full on opiate
not much used
CampyloBacter Jejuni
What is it
Where do you get it
What kills it
It’s an S-shaped Gram (-) Rod
Associated with undercooked contaminated poultry as it is normal flora in the avian gut
Erythromycin is ABX of choice
Side Effect of Sumitriptan/ Imitrex
(and all Triptans)
Chest Tightness
It’s a potent vasoconstrictor. Not for folks with angina, CAD, HTN
